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Dialysis duel: does higher fluid volume or lower sodium improve patient outcomes?

NCT ID NCT07717255

Recruiting now Knowledge-focused Sponsor: East and North Hertfordshire NHS Trust Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This observational study looks at how different settings in haemodiafiltration (a type of dialysis) affect people with kidney failure. It compares high versus low fluid exchange volumes and two different sodium concentrations in the dialysis fluid. Researchers will track toxin removal, symptoms, cognitive function, nutrition, and fluid balance over a year to find the best approach.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could help refine dialysis prescriptions to improve patient well-being and reduce complications.
What could go wrong
As an observational study, it cannot prove cause and effect. Results may not apply to all dialysis patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

end stage renal failure Malnutrition nutritional deficiency disease nutritional disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FLUID BALANCE OUTCOMES HAEMODIAFILTRATION HAEMODIALYSIS MALNUTRITION (CALORIE) NUTRITION PATIENT REPORTED OUTCOME MEASUREMENTS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lister Hospital, East and North Hertfordshire NHS Trust

    RECRUITING

    Stevenage, Hertfordshire, SG1 4AB, United Kingdom

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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