East And North Hertfordshire Nhs Trust

This study investigates whether a blood test measuring clotting and clot-busting markers can predict complications in patients undergoing aortic valve replacement. Researchers will follow 750 adults with aortic stenosis who receive either surgical or catheter-based valve replacem…

This trial compares two devices that inflate the abdomen during robotic prostatectomy for prostate cancer: the AirSeal® Insufflation System and the Stryker PneumoClear Insufflator. The goal is to see which one leads to less pain during and after surgery. One hundred men scheduled…

This study investigates whether Manuka honey can help reduce pain after tonsillectomy (surgery to remove the tonsils). Adults undergoing the procedure will take either honey or a placebo syrup three times daily for 14 days, alongside standard pain medication. The goal is to see i…

This observational study looks at factors that influence bicarbonate levels in people on maintenance hemodialysis for end-stage renal disease. Researchers will collect data on demographics, medical history, diet, and dialysis details, and measure bicarbonate levels before and aft…

This observational study looks at how different settings in haemodiafiltration (a type of dialysis) affect people with kidney failure. It compares high versus low fluid exchange volumes and two different sodium concentrations in the dialysis fluid. Researchers will track toxin re…

This study looks at how a protein called β2-microglobulin builds up in people with kidney failure and how it changes during and after dialysis. Researchers will take blood samples from 30 dialysis patients at multiple time points to track the protein's levels. The goal is to crea…