Blood test could predict clot risk after heart valve surgery

NCT ID NCT04234841

Recruiting now Diagnosis Sponsor: East and North Hertfordshire NHS Trust Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time

Summary

This study investigates whether a blood test measuring clotting and clot-busting markers can predict complications in patients undergoing aortic valve replacement. Researchers will follow 750 adults with aortic stenosis who receive either surgical or catheter-based valve replacement. The goal is to identify those at higher risk for blood clots, strokes, or other serious events, and to determine when that risk is greatest.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: blood test
What this could lead to: If successful, this blood test could help doctors identify patients at high risk of blood clots after aortic valve replacement, potentially preventing strokes and heart attacks.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly improve outcomes. The biomarkers may not reliably predict complications in all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve disorder aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC STENOSIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

East and North Hertfordshire NHS Trust
RECRUITING

Stevenage, Hertforshire, SG1 4AB, United Kingdom

Contact Phone: •••-•••-•••• Email: •••••@•••••

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