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Could a spoonful of honey ease Post-Surgery pain?

NCT ID NCT06275698

Symptom relief Sponsor: East and North Hertfordshire NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study investigates whether Manuka honey can help reduce pain after tonsillectomy (surgery to remove the tonsils). Adults undergoing the procedure will take either honey or a placebo syrup three times daily for 14 days, alongside standard pain medication. The goal is to see if honey improves pain control and recovery, offering a simple, low-cost alternative to conventional painkillers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Manuka honey
What this could lead to
If it works, this could offer a low-cost, natural option to help manage pain after tonsillectomy, potentially reducing the need for painkillers.
What could go wrong
This is a small, early-stage trial, and previous evidence is mixed. The honey may not prove more effective than placebo, and some people may have allergies or dislike the taste.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult (≥18years old at the time of giving consent) * Consented and listed for bilateral tonsillectomy or adenotonsillectomy * Tonsillectomy performed within the trial study period Exclusion Criteria: * Any concurrent Head \& Neck (H\&N) malignancy * Unilateral tonsillectomy * Pregnancy * Concurrent pharyngeal or upper aerodigestive tract biopsy * Robotic tonsillectomy * Previous H\&N malignancy * Previous H\&N radiotherapy * Type 1/2 diabetes mellitus * Known allergy to bee related products * Known allergy to golden syrup * History of chronic pain * History of fibromyalgia * Current usage of chronic (\>6weeks) analgesia * High-risk anaesthetic patients * Children or adolescents \<18years old * Adults unable to consent for themselves

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Conditions

The condition(s) this trial relates to.

agnosia pain agnosia Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Analgesia Post-surgical pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Lister Hospital

    RECRUITING

    Stevenage, SG1 4AB, United Kingdom

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