Can a targeted nerve block beat spinal morphine for hip surgery pain?

NCT ID NCT07784192

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 25, 2026 · Last updated Aug 27, 2026 · Updated 2 times

Summary

This trial asks whether adding morphine to spinal anesthesia or using an ultrasound-guided nerve block provides better pain control after hip surgery. Sixty-four adults having hip replacement or hip fracture surgery will be randomly assigned to one of the two methods. Researchers will compare pain scores, total morphine use, and side effects during the first 48 hours after surgery to see which approach reduces opioid needs and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Morphine added to spinal anesthesia or an ultrasound-guided pericapsular nerve group (PENG) block
What this could lead to
If one method works better, it could point to a way to ease pain after hip surgery while reducing opioid use and side effects.
What could go wrong
This is a small, early-stage comparison, so results may not apply to everyone. Both methods carry risks like nausea, breathing problems, or nerve block complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 to 65 years * American Society of Anesthesiologists physical status I, II or III * Scheduled for unilateral hip surgery under spinal anesthesia, including hip fracture surgery and hip replacement surgery * Able to understand and use the Visual Analog Scale and the patient-controlled analgesia device * Written informed consent Exclusion Criteria: * Refusal to participate * Known allergy or hypersensitivity to local anesthetics, morphine or paracetamol * Any contraindication to spinal anesthesia, including coagulopathy, ongoing anticoagulant therapy, thrombocytopenia, infection at the puncture site, or raised intracranial pressure * Local infection or previous surgery at the pericapsular nerve group block site * Chronic opioid use or history of substance use disorder * Chronic pain requiring regular analgesic treatment before surgery * Cognitive impairment, psychiatric disorder or communication difficulty preventing use of the pain scales * Pre-existing neurological deficit in the operative lower limb * Body mass index above 40 kg/m² * Pregnancy or breastfeeding

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

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  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Selcuk University Hospital

    RECRUITING

    Konya, Selcuklu, Turkey (Türkiye)

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