Can a targeted nerve block beat spinal morphine for hip surgery pain?
NCT ID NCT07784192
First seen Aug 25, 2026 · Last updated Aug 27, 2026 · Updated 2 times
Summary
This trial asks whether adding morphine to spinal anesthesia or using an ultrasound-guided nerve block provides better pain control after hip surgery. Sixty-four adults having hip replacement or hip fracture surgery will be randomly assigned to one of the two methods. Researchers will compare pain scores, total morphine use, and side effects during the first 48 hours after surgery to see which approach reduces opioid needs and improves recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Morphine added to spinal anesthesia or an ultrasound-guided pericapsular nerve group (PENG) block
- What this could lead to
- If one method works better, it could point to a way to ease pain after hip surgery while reducing opioid use and side effects.
- What could go wrong
- This is a small, early-stage comparison, so results may not apply to everyone. Both methods carry risks like nausea, breathing problems, or nerve block complications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 64 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 to 65 years * American Society of Anesthesiologists physical status I, II or III * Scheduled for unilateral hip surgery under spinal anesthesia, including hip fracture surgery and hip replacement surgery * Able to understand and use the Visual Analog Scale and the patient-controlled analgesia device * Written informed consent Exclusion Criteria: * Refusal to participate * Known allergy or hypersensitivity to local anesthetics, morphine or paracetamol * Any contraindication to spinal anesthesia, including coagulopathy, ongoing anticoagulant therapy, thrombocytopenia, infection at the puncture site, or raised intracranial pressure * Local infection or previous surgery at the pericapsular nerve group block site * Chronic opioid use or history of substance use disorder * Chronic pain requiring regular analgesic treatment before surgery * Cognitive impairment, psychiatric disorder or communication difficulty preventing use of the pain scales * Pre-existing neurological deficit in the operative lower limb * Body mass index above 40 kg/m² * Pregnancy or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Selcuk University Hospital
RECRUITINGKonya, Selcuklu, Turkey (Türkiye)
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