Can a double nerve block spare kids with cerebral palsy from Post-Surgery pain?
NCT ID NCT07801365
First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time
Summary
This trial tests whether combining two ultrasound-guided nerve blocks, one near the knee and one behind the knee, can reduce pain after leg surgery in children with cerebral palsy. Children aged 3 to 18 will be randomly assigned to receive either the nerve blocks plus general anesthesia, or general anesthesia with standard intravenous pain relief. Researchers will measure pain scores and the need for extra pain medication during the first 24 hours after surgery to see if the blocks offer better comfort.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Combined popliteal sciatic nerve block and adductor canal block using 0.25% bupivacaine
- What this could lead to
- If it works, this could give children with cerebral palsy better pain control after leg surgery and reduce their need for opioid painkillers.
- What could go wrong
- This is a small, early-stage trial, so results may not apply to all children. Nerve blocks carry small risks like bleeding, infection, or nerve damage, and the added benefit over standard pain relief is not yet proven.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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3 to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pediatric patients aged 3-18 years * Diagnosis of cerebral palsy * Scheduled to undergo lower extremity surgery * American Society of Anesthesiologists (ASA) physical status II-III * Scheduled for elective surgery * Written informed consent obtained from a parent or legal guardian Exclusion Criteria: * Age younger than 3 years or older than 18 years * Coagulopathy or any contraindication to peripheral nerve block * Known allergy to local anesthetics * Infection at the planned block site
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ankara Etlik City Hospital
Ankara, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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- Can modified music tunes boost balance in kids with cerebral palsy?
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- Can an extra nerve block cut opioid use after knee replacement?