CEREBRAL PALSY

This program gives children under 26 with brain conditions like cerebral palsy or stroke access to umbilical cord blood infusions. The cord blood is given through an IV and may help the brain repair itself. It is not a cure, but aims to improve symptoms and quality of life.

This study tests a special hand exercise program for children aged 6-12 with spastic cerebral palsy. The goal is to see if it improves their grip strength and ability to move objects in their hand. Fourteen children will do the exercises for 10 weeks, and their progress will be m…

This study provides intensive, play-based therapy for children with motor impairments from conditions like cerebral palsy, autism, or brain injury. The therapy involves up to 6 hours a day of guided practice to improve use of weaker arms and hands. Researchers will analyze data f…

This study looks at whether giving iron supplements to children with low iron before hip surgery can lower their need for blood transfusions and improve recovery. The trial includes 180 children aged 0-18 who are scheduled for a specific type of hip surgery, many of whom have cer…

This study tests whether starting therapy before age 2 can lessen the effects of cerebral palsy in babies with certain brain injuries. About 66 infants will receive a home-based program with parent coaching and professional support. The goal is to improve motor skills and reduce …

This study is testing whether giving magnesium sulfate to pregnant women at high risk of preterm birth can prevent cerebral palsy in their babies. Researchers will compare the magnesium treatment against a placebo in 138 women between 32 and 35 weeks of pregnancy. The main goal i…

This study tests whether a mobile health system can help people with chronic conditions like spinal cord injury, cerebral palsy, spina bifida, or traumatic brain injury improve their wellness and self-management skills. About 160 participants aged 12 and older will use the system…

This study explores whether a mild, non-invasive electrical stimulation on the back can reduce spasticity (muscle stiffness) in children with cerebral palsy. About 30 children aged 5 to 17 will do movement exercises and receive gentle stimulation that feels like a light tap. Rese…

This study tests whether a virtual reality walking program at home is feasible and helpful for children aged 6 to 17 with conditions like cerebral palsy, neuromuscular diseases, or obesity. Participants use a special treadmill and VR headset for about 30 minutes, three times a we…

This study compares two sequences of active therapy delivered via telemedicine to standard care in infants aged 4-13 months with cerebral palsy or high risk. The goal is to improve arm movement and parenting skills. Researchers will measure changes in fine motor function and pare…

This study explores whether using a power ride-on toy can encourage children with cerebral palsy to use their weaker arm and hand more often. Ten children will participate in a 6-week program where they drive the toy while wearing a mitten on their stronger hand. The goal is to s…

This study tests whether a non-invasive device that stimulates the vagus nerve, combined with arm exercises, can safely help improve arm and hand movement in 10 adolescents with spastic cerebral palsy. The main goal is to check for side effects and see if the therapy is practical…

This study tests a motor training program called 'Let's Move' for infants aged 3-8 months who are at high risk for cerebral palsy. The goal is to see if the program is practical and acceptable for families, and whether it may improve motor skills. About 35 infants will participat…

This study looks at whether adding one session of whole-body vibration to treadmill training can help children with cerebral palsy walk better and reduce leg muscle stiffness. About 20 children aged 6 to 17 with spastic cerebral palsy who can walk will participate. The goal is to…

This study tests a new therapy called MOBILE to help children with cerebral palsy walk better. The goal is to see if children and families find the therapy helpful and easy to do at home. Fourteen children will try the therapy for 30 hours over 6 weeks and share their experiences…

This study will see if a 10-week adapted dance program helps children with cerebral palsy improve their balance, walking ability, and quality of life. About 20 kids aged 4 to 17 with mild to moderate CP will take part. The program uses action-observation principles to guide movem…

This study tests whether a special neck brace can help children with cerebral palsy improve their head and neck movement. Researchers will work with 30 children over 12 training sessions, measuring their progress right after and again 3 months later. The goal is to see if the bra…

This study tests a new therapy that combines thinking, sensing, and moving to help children with cerebral palsy improve hand and arm function. The study will include 32 children aged 6-12. Half will receive the new therapy plus standard physical therapy, and the other half will r…

This study looks at whether aquatic therapy in a warm pool can help children ages 3-9 who have movement problems from conditions like cerebral palsy. The children will attend pool sessions twice a week for ten weeks, focusing on swim safety, arm function, and daily self-care. Res…

This study tests a therapy called HABIT-ILE that combines hand, arm, and leg exercises for children with spastic cerebral palsy. The goal is to see if it improves both movement and thinking skills like memory and attention. 42 children will receive 90 hours of therapy and be comp…

This study tests whether specially designed video games (serious games) can improve balance, memory, and quality of life in 30 children with cerebral palsy. The games combine movement and thinking tasks, offering a fun way to enhance traditional therapy. Researchers will measure …

This study looks at whether letting children with disabilities (like autism or cerebral palsy) help set their own therapy goals leads to better results. About 96 kids aged 5-12 and their therapists will either use a special child-focused goal-setting method called ENGAGE or conti…

This study tests two new ways to help children with cerebral palsy walk better. First, it looks at whether targeted ankle resistance training improves muscle control and mobility more than standard physical therapy. Second, it tests if a robotic ankle brace that adapts to each ch…

This study tests whether a special brace called SPIO Core-Max helps infants aged 6 to 18 months with cerebral palsy improve their head, trunk, and arm control. Researchers will measure changes in posture and quality of life over 6 months. The goal is to see if this simple support…

This study tests whether behavioral coaching, combined with wearable activity monitors, can help people with cerebral palsy take more steps each day. Researchers will track changes in walking speed, balance, and brain activity in 32 participants. The goal is to find a simple, non…

This study tests a program called Therapy Together for young children (3 months to 5 years) with cerebral palsy who have limited hand use on one side. The program uses gentle exercises and activities over 8 weeks to improve hand function and daily skills. Researchers want to see …

This study tests whether adding whole-body vibration to standard serial casting (weekly leg casts) can improve ankle movement faster in children with cerebral palsy. About 45 children aged 3–17 who need ankle casting will participate. The goal is to see if this combination reduce…

This study tests whether adding playful nerve-mobilization activities to standard physical therapy can improve hand grip strength and dexterity in children with cerebral palsy. About 34 children aged 6 to 12 with diplegic CP will be randomly assigned to either routine therapy alo…

This study compares two ways of making ankle-foot braces (AFOs) for people with leg weakness from conditions like cerebral palsy, stroke, or spinal cord injury. The traditional method uses a plaster cast, while the newer method uses 3D scanning and printing. Researchers want to s…

This study tests a robotic leg brace (exoskeleton) designed to improve walking in children aged 3 to 17 with conditions like cerebral palsy, spina bifida, muscular dystrophy, or incomplete spinal cord injury. The device can assist or resist leg movement during walking. The trial …

This study aims to find out if adults with cerebral palsy experience changes in their brain and spinal cord structure over time. Researchers will analyze past and new MRI scans from 30 participants aged 18-80 to see if brain shrinkage relates to loss of function. The goal is to b…

This study uses safe brain imaging techniques (NIRS and EEG) to see which parts of the brain are active during movement in people with cerebral palsy and healthy volunteers. Researchers hope to learn how the brain controls muscles differently in cerebral palsy, which could lead t…

This study looks at a special clinic designed to help adults with conditions like cerebral palsy, spina bifida, or developmental disabilities get better, ongoing care. Many of these people face a "cliff" when they leave children's healthcare and struggle to find adult doctors who…

This study aims to create and improve methods for measuring arm and hand movements in infants, including those with perinatal stroke or cerebral palsy. Researchers will analyze video recordings and developmental tests from 80 children, both with and without motor challenges. No t…

This study looks at sleep quality in children with cerebral palsy (CP) and how it affects the well-being of their caregivers. Researchers will survey 200 children aged 2-18 with CP and their primary caregivers using questionnaires about sleep, daily function, and caregiver stress…

This study tests whether small wearable sensors (IMUs) placed in shoes and on the body can accurately measure walking in children. Researchers will first validate the sensors in healthy children aged 7–17, then in children with cerebral palsy who can walk without aids. The goal i…

This study tests whether a virtual version of the Abecedarian Approach, an early learning program, works as well as in-person sessions for children aged 0-5 who had a brain injury at birth (HIE) or were born very prematurely. Researchers will enroll 225 families in rural areas to…

This study looks at a small leg muscle called the plantaris and its role in treating tight ankles (ankle equinus) in children aged 4-17. About 42 kids having surgery for this condition will have the plantaris and larger calf muscles lengthened in a random order. The goal is to se…

This study uses MRI scans of babies while they sleep naturally to understand how the brain develops in both healthy infants and those at risk for cerebral palsy. Researchers aim to find early signs of brain damage that could lead to faster diagnosis and treatment. About 200 infan…

This study is testing a new, non-invasive sensor to detect lung problems in 250 children with severe cerebral palsy. The goal is to create a simple screening tool that can spot breathing issues early and see how lung health relates to spine curvature. No treatment is given—the st…

This study looks at how hand sensation (like touch and vibration) affects daily activities in children with cerebral palsy aged 6-15. Researchers will compare 12 children with cerebral palsy to 12 typically developing children using tests of sensation and hand function. The goal …

This study follows 100 infants diagnosed with or at high risk for cerebral palsy (CP) over their first two years of life. Researchers will track changes in motor skills, speech, thinking, and other areas to understand how CP naturally progresses. The goal is to gather knowledge t…

This study is creating a shared database of children who have had deep brain stimulation (DBS) for conditions like dystonia, epilepsy, or Tourette syndrome. By collecting information from multiple hospitals, researchers hope to learn which children benefit most, which brain targe…

This study follows 500 children with cerebral palsy who are having leg or spine surgery. Researchers want to understand how pain changes over time and what factors lead to long-term pain. Participants will fill out surveys and do sensory and movement tests before and after surger…

This study looks at how movement and thinking skills are linked in people with brain damage from conditions like cerebral palsy or stroke. Researchers will use a robotic tool to measure arm movements and thinking tasks more precisely. The goal is to improve diagnosis and create b…

This study will follow 1000 babies with brain injuries to create a computer model that helps doctors predict if a child will develop cerebral palsy and how severe it might be. Parents will fill out two online questionnaires about their experiences. No extra tests are needed for t…

This study is building a national database of people with cerebral palsy (CP) in Switzerland. Researchers will collect information on diagnosis, treatments, and daily life from up to 15,000 participants. The goal is to use this data to improve care and quality of life for childre…

This study tests whether brain-computer interfaces (BCI) can be used at home by children aged 5-18 with severe physical disabilities, such as cerebral palsy or brain injury. The goal is to help them achieve personal goals, like communicating or playing. Researchers will also see …

This study aims to understand how the brain and spinal cord work differently in people with cerebral palsy compared to those without. Researchers will use brain scans and mild electrical stimulation to measure activity. The goal is to learn more about the condition, not to provid…

This study aims to better understand how children and young adults with cerebral palsy move by using advanced sensors like ultrasound, brain wave caps, and muscle stickers. Participants aged 5 to 25 will perform simple movements with and without a robotic leg brace. The goal is t…

This study is testing a new smartphone app that can analyze how children with cerebral palsy move, like jumping or walking. The goal is to see if the app works as well as the expensive motion-capture systems used in hospitals. If it does, families could use it at home to help doc…

This study is collecting information from 200 people with cerebral palsy, multiple sclerosis, stroke, fibromyalgia, or similar nerve disorders to see how the EXOPULSE suit affects their balance and walking over time. Participants will be followed during routine care, and research…