Spinal zaps and drug combo aim to boost mobility in kids with cerebral palsy

NCT ID NCT07433023

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a 16-week program of spinal stimulation (using electrodes on the skin) combined with walking or activity training can improve movement in children with cerebral palsy. Some participants can also choose to receive a single injection of a drug called 5-Azacitidine or a placebo to see if it adds extra benefit. The trial includes 80 children aged 4 to 17 with different levels of mobility.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcutaneous spinal stimulation and 5-Azacitidine (a drug)

What this could lead to

If it works, this could point toward a new way to improve walking and movement in children with cerebral palsy.

What could go wrong

This is a Phase 2 trial with only 80 participants, so results are early and may not apply to everyone. The drug part is optional and small, so its effect is uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shirley Ryan AbilityLab

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact