CEREBRAL PALSY

This study follows 25 people aged 2 to 65 with chronic brain injury (HIE) or cerebral palsy who have chosen to receive an experimental gene therapy abroad. The therapy is given as a nasal spray and delivers 15 genes meant to repair brain cells, reduce inflammation, and improve mo…

This study gave one person with severe cerebral palsy eight infusions of their own stem cells, taken from fat tissue. The goal was to see if this treatment could improve their quality of life when standard options had failed. The approach is experimental and only available to tho…

This study tests whether stem cells from donated umbilical cords can improve movement and thinking skills in children with cerebral palsy. About 78 children aged 6 months to 3 years will receive either stem cells plus a special liquid, stem cells alone, or standard care. The goal…

This study compares two ways of delivering 'Therapy Together,' an intensive program where caregivers and young children (ages 3 months to 5 years) with cerebral palsy work together to improve upper limb function. About 37 children will participate. The goal is to see which method…

This study looks at whether using a passive kinesiotherapy device on the legs for 30 minutes can reduce spasticity (muscle tightness) and improve walking in people with conditions like cerebral palsy, stroke-related weakness, or spinal cord issues. About 80 participants will have…

This study explores whether cognitive behavioral therapy (CBT) delivered in virtual group sessions can help adults with cerebral palsy who have chronic pain. Researchers want to see if this approach is practical and if participants stick with it over 12 weeks. The goal is to redu…

This study compares robotic exoskeleton gait training to traditional physical therapy in 64 adolescents and young adults with cerebral palsy. Participants undergo walking tests, brain scans, and reflex measurements before and after training to see which approach improves mobility…

This study tests whether an 8-week power wheelchair training program helps children with severe cerebral palsy improve their driving skills and independence. Sixteen children who cannot walk or push a manual wheelchair will be randomly assigned to either the training or usual car…

This study tests an intensive physical therapy program for children aged 7 to 17 with cerebral palsy who can walk. The program focuses on building strength, power, and walking ability through group sessions. Researchers will measure improvements in muscle strength, walking speed,…

This study tests whether a specialized walking training program can help teens and young adults with cerebral palsy move better. About 120 participants with cerebral palsy will undergo the training, while a separate group of typically developing peers will serve as a comparison. …

This study tests a robot called the CPWalker to see if it can help children and teens with cerebral palsy improve their walking. About 30 participants aged 11 to 21 will use the robot in training sessions. Researchers will measure walking speed and endurance to see if the robot h…

This study tests whether a 12-week play-based training program, including the use of special three-wheeled running bikes, can improve movement and physical activity in 20 children aged 2-5 with cerebral palsy. Kids will take part in group sessions once a week and do exercises at …

This study tests whether a very mild, painless electrical stimulation to the legs can help children and young adults with cerebral palsy keep their balance during everyday movements like standing up, walking, and turning. Participants aged 10 to 21 will perform these tasks with a…

This study compares two physical therapy approaches for children aged 8-24 months with or at high risk for cerebral palsy. One method focuses on sitting, reaching, and problem-solving, while the other targets general motor skills. The goal is to see which therapy improves sitting…

This study aimed to create a database of high-frequency brain signals to better understand epilepsy, migraines, and other brain conditions. It planned to use advanced software to map brain functions in healthy volunteers. However, the study was withdrawn before enrolling anyone, …

This study watches people with brain conditions like traumatic brain injury, cerebral palsy, or Alzheimer's who choose to get special nasal treatments with stem cells or exosomes. Researchers do not give the treatment but collect safety data and measure inflammation markers in th…

This study looks at whether a play-based test of arm and hand movements, called the Melbourne Assessment-2, works just as well when done through telehealth as in person. About 35 children with hemiplegic cerebral palsy, ages 2 to 10, will attend one in-person visit and one telehe…

This study looks at whether a powered wheelchair that can lift a child to a standing position helps them take part in more activities. It includes children aged 5 to 17 with conditions like cerebral palsy, spinal cord injuries, or genetic disorders who cannot walk. The goal is to…

This study aims to understand why constipation is common in children with cerebral palsy and what factors make it worse. Researchers will look at diet, physical activity, and caregiver stress in 100 children aged 4-18. No treatments are given—just questionnaires and diaries to ga…

This study tests a program called Skills on Wheels that teaches children who use manual wheelchairs how to move around safely and independently. The goal is to see if training improves their wheelchair skills, confidence, and social participation. Four children with conditions li…