CEREBRAL PALSY

This study tested an early, intensive therapy program called HABIT-ILE in 36 preschool children (ages 1-4) with bilateral cerebral palsy. The therapy focuses on coordinated use of both hands and legs through structured activities. Researchers measured changes in gross motor funct…

This study tested a Norwegian intensive habilitation program for children aged 2-6 with severe cerebral palsy or similar brain damage. The program aimed to improve the child's daily living skills and empower parents. 93 children and their families took part in a randomized trial …

This study tested a 'blended care pirate group' for children aged 2.5 to 8 with unilateral cerebral palsy. The program combines on-site therapy sessions with home-based training, where children wear a sling on their less-affected arm and do play-like activities to improve use of …

This study tested whether a single infusion of a child's own stored umbilical cord blood could improve motor skills in children with spastic cerebral palsy. Sixty-three children aged 1 to 6 years received either cord blood or a placebo, and their gross motor function was measured…

This completed study tested a special balance training that uses controlled pushes or movements to help children with hemiplegic cerebral palsy improve their balance and body awareness. Thirty children aged 8 to 10 years participated. The training aims to help them react quickly …

This study tested whether multisensory environment stimulation therapy (a specially designed room with controlled lights, sounds, and textures) can improve balance in children aged 9 to 12 with spastic hemiplegic cerebral palsy. 38 children participated, and the therapy was added…

This study tested a new type of leg brace designed to help children with cerebral palsy and other movement disorders walk more easily. The brace was custom-made for each child and could be adjusted to provide different kinds of support. Researchers measured how well children walk…

This study tested a sensorimotor program for infants with hypoxic-ischemic encephalopathy (HIE), a brain injury from lack of oxygen at birth. Eleven babies received play-based therapy sessions in the NICU and at home for the first 6 months. The goal was to see if the program was …

This early-stage trial tested a new oral drug called MTR-601 in 89 healthy adults to see if it is safe and how the body processes it. The drug aims to reduce muscle stiffness and spasms, which could help people with conditions like cerebral palsy, multiple sclerosis, or stroke. S…

This study looked at whether a 10-week adapted dance program could improve balance, walking, and quality of life in 13 children with cerebral palsy. Participants attended 20 hours of dance classes designed to be accessible. The goal was to see if the program was both helpful and …

This study looked at whether an 8-week core muscle strengthening program could improve head and trunk control in 38 non-ambulatory children (ages 4-10) with spastic cerebral palsy. Children did 24 therapist-led sessions with exercises like bridging and sitting on a therapy ball. …

This study looked at whether special breathing exercises could help children with cerebral palsy (ages 5-18) breathe better, improve their balance, arm use, and swallowing. Twenty children with mild to moderate CP took part. The goal was to see if these exercises could make every…

This study tested whether special video games controlled by muscle signals (EMG) can improve walking in children with cerebral palsy. Thirty children aged 2 to 10 with mild to moderate CP played these games alongside physical therapy. The goal was to help them better control ankl…

This study tested whether robotic gait training (using a device called Lokomat) or standard physical therapy, or a mix of both, helps children with cerebral palsy walk better. 68 children aged 5-18 participated in 16 sessions over 8-10 weeks. Researchers measured changes in motor…

This study tested a special nerve-stretching technique (neural mobilization) against standard physical therapy in 40 children aged 5-18 with cerebral palsy and leg spasticity. The goal was to see if it improves joint movement, motor function, and pain. The results may help guide …

This study tested whether shining a special light (photobiomodulation) on the calf muscles can reduce spasticity in children with cerebral palsy. Twelve children aged 2 to 18 received either real or placebo light therapy once a week for two months, alongside their usual care. The…

This study tested a home-based therapy program for infants and toddlers with cerebral palsy, where parents delivered daily exercises guided by a therapist. Twenty children aged 3 to 24 months participated over 18 weeks. The goal was to improve hand function and make therapy easie…

This study tested a drug called valbenazine to see if it can reduce jerky, uncontrolled movements (chorea) in people with cerebral palsy. The trial included 86 children and adults whose medical condition was stable. Participants received either valbenazine or a placebo for 14 wee…

This study tested whether a 6-week home-based virtual reality exercise program is acceptable and beneficial for young people with cerebral palsy who are overweight and inactive. Four participants used a VR headset to play active games. Researchers measured changes in body composi…

This study tested whether a robotic walking device (Lokomat) can improve how children with cerebral palsy or other brain injuries walk. Fifty-nine children completed the program, and researchers measured changes in walking speed, step length, and other movement patterns. The goal…

This pilot study tested a community-based group programme called 'Encompass' for parents of children under 5 with complex neurodisability. Fifteen parents in East London attended ten group sessions over six months. The study aimed to see if the programme was feasible and acceptab…

This study tested a treatment called functional electrical stimulation (FES) in 11 children aged 3-6 who had a stroke around birth and have trouble using one arm. FES uses small electrical currents to make weak muscles move, helping kids practice reaching and grasping. Researcher…

This study tested a high-intensity home exercise program for children with cerebral palsy, using rhythmic arm movements set to music. 42 children aged 6-17 participated, with parents helping to ensure safety. The goal was to see if this fun, accessible program could improve cardi…

This study tested whether Nordic walking—walking with poles like ski poles—can improve walking symmetry in children with hemiparesis due to cerebral palsy. Forty children aged 6-10 participated in a 3-month program combining physical therapy and Nordic walking. The goal was to se…

This pilot study tested the Petö Method, a comprehensive educational therapy, in 13 children aged 4 to 9 with spastic cerebral palsy. The therapy improved gross motor function, including arm and leg movement and postural control, beyond what is considered a meaningful change. The…

This study tested a home-based program for children with cerebral palsy who have trouble chewing. Twenty-two children did chewing exercises, and half also watched videos of chewing actions at home with a therapist's guidance. The goal was to see if adding video observation improv…

This small study looked at whether a special ballet class could help children with cerebral palsy improve their movement and thinking skills. Nine children aged 9 to 15 took part in the dance program. The goal was to see if the program was enjoyable and helpful for coordination, …

This study tested a home-based therapy program that uses sensors to help children with cerebral palsy improve the use of their arms and hands. The therapy, called Tele-HABIT, involves structured play activities done at home under remote guidance. The trial included 29 children ag…

This small study looked at whether metformin, a diabetes medicine, is safe and practical for children aged 5 to 18 with cerebral palsy. Only 3 children took part, and the main goal was to see if families would join and stick with the treatment. Researchers also checked if metform…

This study tested whether adding Xbox Kinect video games to standard therapy could improve hand function and daily activity participation in 24 children aged 7-13 with hemiparetic cerebral palsy. Half received standard therapy plus gaming sessions, while the other half had standa…

This study tested whether combining virtual-reality cycling training with noninvasive brain stimulation could improve upper limb motor function in 36 children and young adults with cerebral palsy. Participants used a virtual-reality bike while receiving either repetitive transcra…

This study tested whether wearing a special pressure sleeve for 6 months could improve hand function in children with cerebral palsy. 101 children aged 5 to 10 took part. The sleeve, made of a stretchy material, was designed to provide gentle pressure to the arm. The main goal wa…

This study looked at whether injecting botulinum toxin into two leg muscles (rectus femoris and semitendinosus) can improve walking and reduce stiffness in children with cerebral palsy. 23 children aged 7 to 17 who could walk (with or without aids) took part. Researchers measured…

This study tested two types of exercise—moderate steady training and high-intensity interval training—in 30 children with spastic diplegia (a form of cerebral palsy) aged 3 to 5. The goal was to see which better improves walking, energy use, and daily movement. Children were spli…

This study tested whether adding a multi-component home training program to standard care helps children with cerebral palsy recover better after lower leg tendon release surgery. Forty children aged 4-18 who could walk participated. The study measured movement, pain, fear of mov…

This study tested whether Action Observation Therapy—watching a movement and then doing it—can reduce spasticity and improve motor skills, balance, and participation in children with cerebral palsy. 36 children aged 5-13 with spastic diplegia or hemiplegia took part. The therapy …

This small study tested whether a robotic bodyweight support system combined with smart insoles that beep at the right time can help adults with cerebral palsy walk better. Five adults completed 6 training sessions. Researchers measured walking speed, endurance, and joint movemen…

This study tested a new type of mobility training (called dynamic supported mobility) for infants and toddlers with cerebral palsy. The goal was to see if it helps improve movement and balance better than standard care. 42 children aged 12 to 36 months took part. The study compar…

This study tested a 12-week exercise program set to music for adults with physical disabilities like spinal cord injury, stroke, or Parkinson's disease. Participants exercised three times a week via video calls, doing movements adapted to their ability. The goal was to see if the…

This study tested whether giving children a single dose of dexamethasone before a nerve block for ankle or foot surgery could extend pain relief and reduce the need for strong painkillers like opioids. 90 children took part, receiving either a small or large dose of dexamethasone…

This study tested a 3-week intensive program of play-based physical therapy for children with cerebral palsy. Seven children aged 2 to 12 took part in activities like treadmill walking and overground walking. Researchers measured changes in movement, daily skills, and quality of …

This study looks at how touch, vibration, and position sense in the hands and arms affect daily activities in children with cerebral palsy. Researchers will compare 12 children with CP to 12 typically developing kids aged 6 to 15. They use simple tests like tuning forks and monof…

This study followed 60 infants at high risk for cerebral palsy from birth to 18 months to see how they learn to move. Researchers used wearable sensors and a robotic crawler to measure leg movements, crawling, and walking. The goal was to understand how motor skills develop or ar…

This study looked at 10 school-aged children with cerebral palsy to see if their hand function is related to their school grades and performance. Researchers measured hand ability using standard tests and compared them to report card grades and teacher evaluations. The goal was t…

This study looked at 62 children with cerebral palsy (ages 2-18) and their primary caregivers to understand how the children's sleep problems relate to caregiver burden and mental health. Researchers used questionnaires to measure sleep quality in both children and caregivers, al…

This study looked at 44 preterm infants born before 28 weeks to see if their brain activity and general movements could predict cerebral palsy. Researchers used EEG and movement recordings to find patterns linked to the condition. The goal was to improve early diagnosis and help …

This study looked at how young children with Down syndrome, cerebral palsy, and other motor delays move and explore when using a powered mobility device called the Explorer Mini and a bodyweight support system. Sixteen children who could sit upright but not walk 10 feet on their …

This study tested whether a heart-rate based index (ANI) can detect pain in 17 children with cerebral palsy during injections and physical therapy. Researchers measured heart rate changes before and after painful procedures and compared them to standard pain scores. The goal was …

This completed study looked at 40 children with cerebral palsy to see if the quality of their early movements (around 10-20 weeks after birth) could predict how well they would move later in childhood. Researchers used video recordings to score early motor patterns and compared t…

This completed study from Dijon University Hospital followed 60 parents of infants at high risk for cerebral palsy after NICU discharge. Researchers measured parental stress and healthcare use at 4, 9, and 24 months corrected age using questionnaires. The goal was to understand h…

This study looked at whether doing virtual reality exercises with other people (multi-player) is more motivating than doing them alone. It included 86 participants: healthy teens, children with motor disorders, and older adults with conditions like stroke or COPD. Researchers mea…

This study followed 188 children who had seizures shortly after birth to see how they develop over time. Researchers measured thinking skills, behavior, and daily function. The goal is to understand which children are at higher risk for conditions like cerebral palsy or intellect…

This study looked at how trunk control, balance, and upper body function are connected in children with cerebral palsy. Researchers measured these abilities in 53 children and compared them to healthy kids. The goal was to better understand these relationships to guide future the…

This study measured how much energy children with cerebral palsy use while walking, with and without harness support. 34 children aged 8-17 walked on a treadmill while researchers tracked their oxygen use and movement. The goal was to understand what makes walking so tiring for t…

This study looked at 40 children with cerebral palsy, ages 4 to 8, to see if anxiety is linked to worse balance, muscle stiffness, and movement. Researchers measured anxiety, spasticity, balance, and gross motor function. The goal was to understand these connections better, not t…

This study looked at 78 children with cerebral palsy (CP) aged 6 to 12 to see how well they could sense the position of their trunk (body awareness) and how that relates to their trunk control and ability to do daily tasks independently. Researchers used simple devices to measure…

This study tested whether two devices — a knee traction dynamometer and a non-invasive muscle sensor — can reliably measure muscle strength and activity in children with cerebral palsy. Twenty children aged 5 to 16 with mild to moderate CP took part. The goal was to see if these …

This completed study looked at whether children with neurodevelopmental disorders (like mitochondrial disease, cerebral palsy, or developmental delay) have fewer small nerve fibers in their skin, which could cause pain. Researchers took small skin biopsies from 203 children—some …

This study tested a special light-and-sensor system (WittySEM) to measure how quickly and accurately children with cerebral palsy can react to visual cues. Twenty children completed memory tasks by touching lighted targets, while cameras tracked their movements. The goal was to s…

This study investigated why humans swing their arms during walking, a common but poorly understood movement. Researchers had 25 participants, including healthy individuals and those with conditions like stroke or Parkinson's disease, walk on a force-sensing treadmill. They measur…

This study looked at 126 children and young adults (up to age 25) with serious, non-progressive neurological diseases like cerebral palsy or brain injury. Researchers wanted to understand the best time to introduce a pediatric palliative care team. They reviewed medical records f…

This study looked at two community-based wellness programs for adults with disabilities like spina bifida, cerebral palsy, spinal cord injury, and traumatic brain injury. Researchers measured changes in health, mood, quality of life, and healthcare costs over up to 24 months. The…