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Ultrasound-Enhanced gel and nerve stretching may ease diabetic foot pain

NCT ID NCT07683338

Completed Symptom relief Sponsor: Syeda Khatoon e Jannat Welfare Foundation Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 23, 2026 · Updated 4 times

Summary

This study tests whether applying pregabalin gel through ultrasound (phonophoresis) combined with nerve flossing exercises can reduce pain and improve sensation in people with diabetic peripheral neuropathy. The trial includes 24 adults aged 40–75 who have chronic nerve pain in their feet. Participants are randomly assigned to receive the combined treatment or a control, and pain levels and sensory function are measured before and after the intervention.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
pregabalin gel
What this could lead to
If effective, this combination approach could offer a non-invasive, drug-sparing way to reduce neuropathic pain and improve sensory function in people with diabetic neuropathy.
What could go wrong
This is a small, early-stage trial with only 24 participants, so results may not apply broadly. The treatment may not outperform standard care, and individual responses can vary.

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Conditions

The condition(s) this trial relates to.

cerebral palsy diabetic neuropathy Mobility Limitation neuralgia spastic diplegia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BILATERAL SPASTIC CEREBRAL PALSY CEREBRAL PALSY DIABETIC NEUROPATHIC PAIN GAIT ABNORMALITY MMOTOR FUNCTION IMPAIRMENT PAINFUL DIABETIC PERIPHERAL NEUROPATHY PERIPHERAL DIABETIC NEUROPATHY SPASTICITY DUE TO CEREBRAL PALSY

Contacts and locations

Locations

  • Syeda Khatoon e Jannat Trust Hospital & Special Education Centre

    Faisalabad, Punjab Province, 3800, Pakistan

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