Cerebral palsy

This trial compares two rehabilitation techniques—constraint-induced movement therapy (CIMT) and proprioceptive neuromuscular facilitation (PNF)—to see which better improves hand dexterity in children with cerebral palsy. The study includes children aged 8 to 13 with moderate men…

This study tests whether combining task-oriented training with functional electrical stimulation (FES) can improve balance and ankle strength in children aged 6-9 with hemiparesis (weakness on one side). Thirty-six children will participate in a structured exercise program three …

This study tests whether placing a deep brain stimulation (DBS) device in the cerebellum is safe for 10 children and young adults (ages 7-25) with severe dyskinetic cerebral palsy. The device delivers electrical pulses to try to improve movement and spasticity. Researchers will a…

This study tests whether a robotic hand device can help people recovering from a stroke improve hand strength and dexterity better than standard physical therapy. Thirty adults with sub-acute stroke (2 weeks to 6 months post-stroke) will be randomly assigned to receive either rob…

This study tests whether a smart ankle-foot orthosis (a brace that gives feedback on walking) can improve mobility in 60 children with cerebral palsy. Some participants can also choose to receive a single injection of 5-Azacitidine, a drug used in cancer, to see if it boosts the …

This study tests whether a 16-week program of spinal stimulation (using electrodes on the skin) combined with walking or activity training can improve movement in children with cerebral palsy. Some participants can also choose to receive a single injection of a drug called 5-Azac…

This study looks at whether giving iron supplements to children with low iron before hip surgery can reduce their need for blood transfusions and improve recovery. The trial includes 180 children aged 0-18 who are scheduled for a specific type of hip surgery, many of whom have ce…

This study tests whether a telehealth program that coaches parents to use adaptive standers can improve physical activity, sleep, and endurance in children ages 1-6 with severe motor delays (like cerebral palsy). Twenty children and their parents will take part in 8 weeks of stan…

This study tests whether starting a personalized home therapy program early (before age 2) can improve motor skills in babies at high risk for cerebral palsy. Researchers will compare children who receive this early program with those who get standard care. The goal is to see if …

This study tests whether injecting a child's own bone marrow cells into the spine, combined with rehabilitation, can improve motor function in children with cerebral palsy from birth injuries. Sixty children aged 1 to 6 years will be randomly assigned to receive either the cell t…

This study tests whether a virtual version of the Abecedarian Approach, an early childhood education program, can help children ages 0-5 who had a brain injury from lack of oxygen (HIE) or were born very prematurely. Researchers will enroll 225 families and measure parent satisfa…

This study tests whether freezing specific nerves (cryoneurolysis) can reduce shoulder pain and improve movement in people with spasticity from conditions like stroke or brain injury. Fifty adults will either receive one session of nerve freezing or one session of Botox injection…

This study tests a surgery that moves a nerve from the neck to help people with arm weakness after a stroke. It is for those whose arm has not improved with rehab. The goal is to see if the surgery can improve arm movement and control.

This study tests whether Cuevas Medek Exercises can improve posture and balance in children with spastic cerebral palsy. 54 children will be randomly assigned to either the new exercises or standard therapy. The goal is to see if these exercises help children control their body p…

This program gives children with brain disorders like cerebral palsy or stroke access to umbilical cord blood infusions. The treatment uses donated cord blood cells to help repair brain damage. Kids up to age 26 with normal immune function may qualify. The goal is to improve symp…

This study tests whether a child's own bone marrow stem cells can safely improve movement and muscle control in cerebral palsy caused by lack of oxygen at birth. Fifty-eight children aged 1 to 10 will be split into two groups: one gets stem cell infusions right away, the other wa…

This study looks at how well a special intensive therapy called ACQUIRE Therapy works for children with motor problems caused by conditions like cerebral palsy, autism, or brain injury. The therapy involves many hours of play-based exercises each day, often with a cast or splint …

This study compares two physical therapy approaches—Dynamic Movement Intervention (DMI) and the Bobath method—in 58 children with spastic cerebral palsy. The goal is to see which therapy better improves motor skills, balance, and trunk control over 12 weeks. Children will be asse…

This study tests a therapy called VOJTA for children aged 2 to 6 with ataxic cerebral palsy, a condition that affects balance and coordination. The therapy uses gentle pressure on specific body areas to activate natural movement patterns. Researchers will compare VOJTA to standar…

This study tests whether dynamic surface exercise training (exercises on unstable surfaces like physio balls) can improve mobility, balance, and coordination in children aged 5-8 with diplegic cerebral palsy. 14 children will be randomly assigned to either the dynamic surface exe…

This study tests whether a child-friendly core exercise program, delivered via video, can improve balance and mobility in children aged 6-12 with spastic cerebral palsy. Half of the 54 participants will do the Fun-Core exercises at home 3 times a week for 8 weeks, while the other…

This study tests a wearable robotic exoskeleton designed to improve walking in children aged 3 to 17 with conditions like cerebral palsy, spina bifida, muscular dystrophy, or incomplete spinal cord injury. The device fits on the legs and can assist or resist movement during walki…

This study tests a program called Therapy Together, where caregivers lead hand therapy exercises for young children with cerebral palsy who have limited use of one hand. The program lasts 8 weeks and aims to improve hand function and daily skills. Researchers will compare these c…

This study is testing whether simple wearable devices can accurately screen for sleep disorders in children with cerebral palsy. About 140 children aged 6 to 15 will wear the devices at home and then undergo a standard hospital sleep test. The goal is to see if the wearable metho…

This study is creating and testing a new questionnaire for caregivers to identify hip pain in children with quadriplegia who cannot communicate verbally. Researchers will first develop the questionnaire with input from experts and parents, then test it with 100 caregivers. The go…

This study is testing a new, non-invasive respiratory sensor (pneuRIP) to detect lung problems in 250 children with severe cerebral palsy. The goal is to see if the sensor can screen for issues like pneumonia or airway blockage, and to understand how lung function relates to spin…

This study tests whether giving magnesium sulphate to pregnant women at high risk of preterm birth can protect their babies from cerebral palsy. About 138 women between 32 and 35 weeks of pregnancy will receive either magnesium or a placebo before delivery. Researchers will then …

This study tests whether a powered leg brace called Agilik can help children with cerebral palsy who walk with bent knees (crouch gait). Forty children will either use the device at home for 2 months or receive standard therapy. Researchers will measure changes in walking enduran…

This study tests a therapy called HABIT-ILE, which uses structured hand and leg exercises, to see if it can improve both motor skills and cognitive functions like memory and attention in children with spastic cerebral palsy. 42 children will receive 90 hours of therapy and be com…

This pilot study tests whether a 10-week treadmill training program combined with blood flow restriction (using cuffs on the legs) can safely improve walking speed in 13 children aged 8 to 18 with cerebral palsy. The children will walk on a treadmill three times a week, gradually…

This study tests whether gentle vibration on the face and neck can reduce drooling and improve muscle tone in children with cerebral palsy. Twenty children will receive either vibration plus standard therapy or a sham treatment. The goal is to see if this simple approach can ease…

This study tests whether home-based video games can improve speech clarity and arm movement in children with cerebral palsy. Fifteen children aged 8-17 will play specially designed computer games for 30 minutes a day, 5 days a week, for 8 weeks. Researchers will measure changes i…

This study tests whether a non-invasive sound wave procedure (focused ultrasound) can safely improve movement and quality of life in 10 children and young adults (ages 8-22) with dyskinetic cerebral palsy. The treatment targets a small area in the brain to reduce involuntary move…

This study is testing whether a non-invasive brain stimulation technique called rTMS, when combined with standard rehabilitation, can improve leg movement and reduce muscle stiffness in children with spastic diplegic cerebral palsy. The study will include 20 children aged 5 to 18…

This study tests whether special speech strategies, like pointing to letters or using rhythm, can help children with cerebral palsy speak more clearly. About 100 kids ages 7 to 17 will practice these techniques with a speech therapist and then have their speech recorded. The goal…

This study tests whether a gentle, quick spinal manipulation can improve heart rate variability in children with cerebral palsy. Twenty children will each receive both the real procedure and a sham (fake) version on separate days. Researchers will measure changes in heart rate pa…

This study tests whether pairing electrical stimulation of the brain's hand area with stimulation of a wrist nerve can improve hand and arm function in adults with hemiplegic cerebral palsy (hCP). Researchers will measure changes in muscle responses and dexterity tasks like movin…

This study tests whether adding motor imagery (mentally practicing movements) and action observation (watching movements) to standard physical therapy can improve gross motor function, upper limb skills, and quality of life in children with unilateral cerebral palsy. Forty-eight …

This study compares two types of therapy—sensory integration therapy and standard physical therapy—to see which one helps children with athetoid cerebral palsy improve their gross motor skills (like walking and balance). About 26 children aged 6 to 12 will take part. The goal is …

This study tests whether adding a sensory walkway to standard physical therapy can improve walking in children aged 5-7 with spastic diplegic cerebral palsy. 44 participants will either receive conventional therapy alone or conventional therapy plus sensory walkway training for t…

This study tests whether adding electrical stimulation to a movement therapy helps children with cerebral palsy use their arms better. 46 children aged 3 to 15 will be split into two groups: one gets the combined therapy, the other gets movement therapy alone. Both groups will ha…

This study looks at whether a three-month stay focused on adapted physical activity can improve the physical fitness and quality of life of children with chronic illnesses, rare diseases, or disabilities who have become physically deconditioned. About 50 children aged 8 to 18 wit…

This study tests whether a non-invasive technique called transcutaneous spinal cord stimulation (tSCS), combined with specific arm and hand exercises, can improve upper limb function in children and young people (ages 12-21) with hemiplegic cerebral palsy. The treatment involves …

This study looks at whether a 10-week plan with a leucine supplement is practical for children with spastic cerebral palsy. It also checks for early signs of muscle growth using ultrasound. Only 5 children will take part to see if they can stick with the supplement and if it affe…

This study tests whether a 24-week Frame Running training program can improve physical function, daily activity, and quality of life in children aged 8-18 with cerebral palsy or similar physical disabilities. Participants start with a low-intensity 12-week period, then move to a …

This study tests a robot suit called Bambini Kids that helps children with cerebral palsy move their legs in a more natural way. The goal is to see if it is safe and can improve walking and daily activities. About 30 children aged 2 to 10 will take part. The robot provides repeti…

This study tests a new therapy called MOBILE to help children with cerebral palsy walk better. Fourteen children will try the therapy for 30 hours over 6 weeks. The goal is to see if the therapy is acceptable and helpful for children and families in a community setting.

This study tests whether a mild, non-invasive electrical stimulation on the back (transcutaneous spinal cord stimulation) can reduce spasticity—stiff, tight muscles—in children with cerebral palsy. Researchers will compare spinal cord activity in 30 children with CP and typically…

This study tests whether a non-invasive brain stimulation technique called rTMS, followed by intensive arm training, can reduce muscle stiffness (spasticity) in children aged 7–18 with hemiplegic cerebral palsy. Twenty participants will receive either real or sham rTMS over 10 da…

This study tests whether adding task-specific electrical stimulation to standard physical therapy can improve upper limb gross motor skills in children aged 2 to 6 with spastic quadriplegia cerebral palsy. Thirty children will be split into two groups: one gets standard therapy, …

This study tests whether a two-week intensive rhythmic dance program can improve learning ability in children with cerebral palsy. Six children aged 6-17 will take dance classes and be assessed repeatedly on motor, cognitive, and social goals. The goal is to see if dance, which c…

This study tests whether remote ischemic conditioning (RIC) — brief cycles of cutting off and restoring blood flow to a limb — combined with balance training can improve balance and spinal reflexes in children with cerebral palsy (CP). Sixteen children aged 8-17 with mild to mode…

This study looks at whether adding whole-body vibration (standing on a vibrating platform) right before serial casting can improve ankle movement in children with cerebral palsy. About 45 kids aged 3-17 will do exercises with or without vibration before getting their weekly cast.…

This study looks at how often a non-invasive treatment called radial extracorporeal shock wave therapy (rESWT) should be given to reduce muscle stiffness in children with cerebral palsy. Forty-five children aged 6 to 14 will receive either real or sham therapy once or twice a wee…

This study looks at whether adding a single session of whole-body vibration to treadmill training can improve walking and reduce muscle stiffness in children with cerebral palsy. About 20 kids aged 6-17 who can walk will participate. The goal is to see if combining these therapie…

This small safety trial tests whether a non-invasive device that stimulates the vagus nerve through the ear can safely improve hand and arm function in 10 adolescents with spastic cerebral palsy. Participants will use the device during upper limb rehabilitation sessions. The main…

This study compares two types of hand therapy for children aged 5-12 with spastic hemiplegic cerebral palsy, a condition that causes stiffness and weakness on one side of the body. One therapy uses both hands together, the other focuses on the affected hand alone. Over 8 weeks, r…

This study tests two new methods to improve hand function in children with cerebral palsy: a virtual reality system called Leap Motion that uses hand-tracking games, and neuromuscular electrical stimulation (NMES) that uses mild electrical pulses to activate muscles. Thirty child…

This study is testing whether targeted ankle resistance training and a smart ankle assist device can improve walking in children with cerebral palsy (ages 8-21). Researchers will measure changes in walking speed, muscle activity, and endurance. The goal is to find better ways to …

This study tests whether simple brain gym exercises—like drinking water, cross crawls, and deep breathing—can improve balance and quality of life in children aged 6 to 8 with spastic diplegia, a type of cerebral palsy. Forty-four children will be split into two groups: one doing …

This study tests whether immersive virtual reality (VR) therapy can improve cognitive, motor, and social skills in children aged 8 to 18 with ADHD, autism, or cerebral palsy. Participants will use the CAREN VR system, which provides interactive exercises with visual, sound, and t…

This study tests whether adding playful nerve-gliding activities to standard physical therapy can improve hand grip strength and dexterity in children with cerebral palsy. About 34 children aged 6-12 will be split into two groups: one gets routine therapy plus play-based hand exe…

This study looks at whether a robotic walking trainer, called Trexo, can help people with walking problems from conditions like cerebral palsy or brain injury. About 120 participants will use the robot in a hospital setting to see if it's practical and helps them reach their pers…

This study tests a new therapy that combines a brain-computer interface (BCI) with electrical stimulation to help children with cerebral palsy move their arms and hands. Eight children aged 12 to 17 will wear a cap that reads their brain signals, and when they imagine moving thei…

This study tests an intensive 2-week rehabilitation program for children and teens with cerebral palsy. The program combines two proven therapies: one that encourages use of the weaker hand and another that trains both hands together. Researchers want to see if this approach impr…

This study tests whether a wearable trunk brace, called the SPIO Core-Max Expedition TLSO, can improve head, trunk, and arm function in infants aged 6 to 18 months with cerebral palsy. Thirty infants will wear the brace for 2 hours daily over 6 months, and researchers will measur…

This study tests whether using a ride-on toy for 6 weeks can help children with cerebral palsy use their weaker arm and hand more. Ten children will wear a mitten on their stronger hand to encourage using the other hand while driving and playing. Researchers will measure changes …

This study tests a new physical therapy program for children with cerebral palsy who have a crouched walking pattern. The therapy focuses on correcting pelvic tilt and strengthening the soleus muscle in the calf, which is often overlooked. Forty children aged 4 to 10 will partici…

This study tests a procedure called cryoneurolysis, which uses cold to temporarily block nerves that cause painful muscle tightness in the shoulder and elbow. It is for people with cerebral palsy who have not found relief from other treatments. The goal is to see if it helps them…

This study tests whether a mixed-reality video game called Bootle Blast can help children aged 6–17 with hemiplegic cerebral palsy improve their arm and hand skills through home-based play. About 46 participants will either start the game right away or wait 12 weeks while continu…

This study tests a new approach called ENGAGE, where children with disabilities (like autism or cerebral palsy) help set their own therapy goals. About 96 kids aged 5-12 and their therapists will be split into two groups: one using ENGAGE and the other using usual therapy. Resear…

This study tests a new home-based program that uses a special treadmill and virtual reality to help children with conditions like cerebral palsy, muscle diseases, or obesity improve their walking. About 30 children aged 6 to 17 will try the program at home for at least 3 sessions…

This study tests whether a 12-week functional power training program (MegaPower) helps children with cerebral palsy achieve their personal participation and activity goals better than usual care. The trial will include 66 children aged 4-12 who can walk with or without help. Rese…

This study looks at two different calf-stretching programs for adults with cerebral palsy who have tight calf muscles and walk slowly. Forty participants will be assigned to one of two stretching routines for one year. The goal is to see if either program can improve walking spee…

This study tests a treatment that uses precise radiation beams to target nerves in the back, aiming to reduce muscle tightness (spasticity) caused by stroke, spinal cord injury, or cerebral palsy. About 22 people will be randomly assigned to receive either the real treatment or a…

This study looks at whether botulinum toxin type A injections can improve hand and leg function and quality of life in 30 children aged 8 to 17 with spastic hemiparetic cerebral palsy. Participants receive one injection and are followed for 12 weeks. The goal is to see if this tr…

This study tests a structured exercise program called task-oriented circuit training in 34 children aged 5-12 with hemiplegic cerebral palsy. The program includes 14 stations targeting walking, balance, and strength. Researchers will measure improvements in walking distance and d…

This study tests whether a free online program from the World Health Organization, called 'Doing What Matters in Times of Stress,' can help reduce anxiety and depression in employees of small and medium-sized Dutch companies. About 518 workers with elevated stress levels will eit…

This study tests whether an intensive, activity-based walking training program can improve movement and quality of life for young children with cerebral palsy who cannot walk on their own. Nineteen children will either receive the training or continue usual care. The goal is to s…

This study tests whether adding a robotic glove to standard hand therapy (CIMT) can improve hand dexterity and grip strength in children aged 6-12 with hemiplegic cerebral palsy. Half of the 34 participants will receive CIMT alone, while the other half will also use a robotic glo…

This study tests a 10-week hand strength training program for 14 children aged 6-12 with spastic cerebral palsy. The goal is to see if it improves their grip strength and ability to manipulate objects in their hand. Researchers will measure changes using a dynamometer and the Mel…

This study tests whether adding a special exercise program (kinesiotherapy) to standard physical therapy can improve arm movement and daily living skills in children aged 8-13 with hemiplegic cerebral palsy. 28 children will be split into two groups: one gets kinesiotherapy plus …

This study tests a special therapy called Cognitive Sensory Motor Training (CSMT) to see if it can improve hand and arm function in children with cerebral palsy. The therapy combines physical tasks with mental exercises to boost coordination and sensory awareness. Researchers wil…

This study tests whether adding a mild electrical stimulation to the skin of the affected hand (called SAES) can improve hand function in children aged 6-18 with hemiparesis (one-sided weakness) due to cerebral palsy or stroke. 34 participants will be randomly assigned to receive…

This study tests whether ankle braces made with 3D scanning and printing work as well as those made the old-fashioned way with plaster casts. About 50 people aged 8 and older with leg weakness from conditions like cerebral palsy, stroke, or spinal cord injury will try both types …

This study tests a new early intervention program for infants aged 4-10 months who are at risk of developing cerebral palsy. The program combines weekly home sessions with caregiver training to support the baby's development and reduce challenges. Researchers will check if the pr…

This study looks at whether a special therapy done at home through video calls can help infants with cerebral palsy use their weaker arm more. About 267 babies aged 4 to 13 months will be assigned to different sequences of the therapy or standard care. The goal is to see if the t…

This study tests whether extracorporeal shock wave therapy (ESWT) can reduce spasticity—stiff, tight muscles—in the wrists of people who had a stroke at least six months ago. Researchers will give 32 participants either ESWT plus standard rehab or just standard rehab. They will u…

This study aims to see if behavioral coaching, using wearable activity monitors, can help people with cerebral palsy increase their daily steps and improve mobility. Researchers will track changes in walking speed, balance, and brain activity in 32 participants. The goal is to fi…

This study tests a motor training program called 'Let's Move' for infants aged 3-8 months who are at high risk for cerebral palsy. The program involves weekly sessions alternating between clinic visits and video telehealth at home for 16 weeks. Researchers want to see if the prog…

This study tests whether a soft back brace that supports the natural curve of the lower back can improve posture, balance, and walking speed in children with cerebral palsy. Twenty-five children aged 6 to 15 with mild to moderate mobility issues will be tested with and without th…

This study tests a special neck brace designed to help children with cerebral palsy improve their head and neck control. The brace uses sensors, springs, and small motors to support and gently guide head movements during training. Researchers will enroll 30 children and measure c…

This study tests whether serious games (special video games that combine movement and thinking) can improve balance, memory, and quality of life in 30 children with cerebral palsy. Kids play daily for 30 minutes over 10 days, alongside their usual rehab. Researchers will measure …

This study uses safe brain imaging techniques (NIRS and EEG) to see how the brain controls movement in people with and without cerebral palsy. Researchers will compare brain activity patterns and test whether biofeedback training can help people with cerebral palsy improve their …

This study is testing a new leg exoskeleton designed by the NIH to help children and young adults with muscle weakness from conditions like cerebral palsy or spinal cord injury. Researchers want to see how well the device works in different real-world settings, like walking on a …

This study uses MRI scans to look at brain and spinal cord structure and function in people with cerebral palsy who experience chronic pain. Researchers hope to find patterns in the brain that are linked to pain and sensory issues. Participants aged 8 and older with cerebral pals…

This study is testing how the drug trihexyphenidyl is processed in the bodies of 40 children aged 5-17 with dystonic cerebral palsy. Researchers want to see if a child's genetic makeup changes how the drug works, which could help create personalized dosing plans. Participants wil…

This study looks at how children and young adults with cerebral palsy move, using special sensors like ultrasound, brain wave caps, and muscle stickers. Researchers want to learn more about movement to improve robotic leg braces that could help people walk better. Participants wi…

This study looks at how children with cerebral palsy (CP) adapt their walking when given feedback from a treadmill, sensors, and a wearable exoskeleton. Researchers want to understand how kids learn new movement patterns and whether training or surgery can improve their walking. …

This study tests a new way to stimulate the brain and a nerve in the arm at the same time to encourage the spinal cord to adapt and improve hand movement. It involves 20 healthy adults who will receive non-invasive stimulation while researchers measure muscle responses. The goal …

Cerebral palsy (CP) is a brain injury that affects movement, but diagnosing it can take up to 2 years. This study follows 600 high-risk infants (premature, brain-injured, or with abnormal exams) across Irish hospitals. Researchers will use EEG sleep tests, protein markers, and co…

This study asks 500 adults with cerebral palsy to fill out questionnaires about their memories of botulinum toxin injections they received as children. Researchers want to learn how effective and painful the treatments felt, how well doctors communicated, and what coping strategi…

This study is looking at whether the brains and spinal cords of adults with cerebral palsy shrink or change over time, which might explain why some people lose function as they age. Researchers will collect and compare past and new MRI scans from 30 adults with CP across the U.S.…

This study looks at how muscles grow and change in children with cerebral palsy (CP) by examining tiny samples from leg muscles. Researchers will compare these microscopic findings with muscle images and movement tests. The goal is to better understand why muscles in CP develop d…

This study tests whether brain-computer interfaces (BCIs) can be used at home by children aged 5-18 with severe physical disabilities, such as cerebral palsy or brain injury. Families receive a BCI kit and participate in 12 virtual coaching sessions over 3-6 months. The goal is t…

This study looks at muscle problems, metabolic issues, and chronic inflammation in adolescents and young adults (ages 14-30) with moderate to severe spastic cerebral palsy. Researchers will compare them to less affected and healthy peers, then have the more affected group do a 12…

This study looks at how botulinum toxin (Botox) injections change muscle structure in children with spastic cerebral palsy. Using advanced imaging like MRI and 3D ultrasound, researchers will measure muscle size, fat content, and stiffness in 51 children. The goal is to understan…

This study aims to better understand the link between motor (movement) and cognitive (thinking) problems in people with brain damage from conditions like cerebral palsy or stroke. Researchers will assess 400 participants aged 3 to 90 using robotic tools and standard tests. The go…

This study is testing whether a smartphone app can accurately measure how children with cerebral palsy move, like jumping and walking. Researchers will compare the app's results with standard motion-capture systems. The goal is to make it easier and cheaper to assess motor skills…

This study looks at 72 children aged 5 to 8 with hemiplegic cerebral palsy to see how well they can use their affected arm and how that relates to their participation in everyday activities. Researchers will measure arm movement quality and compare it to how much the children tak…

This pilot study explores whether adding sound and touch to a standard movement-observation therapy can better activate the brain's mirror neuron system in children with cerebral palsy. Twenty kids with CP and 20 typically developing peers, aged 7-25, will watch videos of actions…

This study looks at videos and sounds from babies to find early clues about conditions like cerebral palsy and autism. About 46 infants who were in the NICU will have their movements and cries recorded at home. Researchers hope to identify patterns that could lead to earlier dete…

This study tests whether small wearable sensors (called IMUs) placed in shoes and on the body can accurately measure how children walk. Researchers will first check the sensors in healthy children aged 7–17, then in children with cerebral palsy who can walk without aids. The goal…

This study looks at how a 2-week, personalized therapy program helps children aged 4-12 with conditions like cerebral palsy, autism, or genetic disorders. Kids get about 2.5 hours of tailored therapy each day, focusing on skills like movement, attention, and communication. The go…

This study is creating a shared database of children who have received deep brain stimulation (DBS) for movement disorders like dystonia, epilepsy, or Tourette syndrome. By pooling data from multiple hospitals, researchers hope to answer key questions about who benefits most and …

This study examines the role of the plantaris, a small calf muscle, in children having surgery for tight ankles (equinus). Researchers will randomly change the order of tendon cuts during surgery to measure how much each contributes to ankle movement. The goal is to understand if…

This study looks at a special clinic called TLC that helps adults with conditions like cerebral palsy, spina bifida, and developmental disabilities get better, coordinated care. Many of these people face a 'cliff' when they leave children's healthcare and struggle to find adult d…

This study is testing whether wearable sensors can accurately measure how people climb stairs. Researchers will compare sensor data to traditional stopwatch timing in healthy volunteers and people with conditions like cerebral palsy, Parkinson's disease, and stroke. The goal is t…

This study is collecting information from 200 people with cerebral palsy, multiple sclerosis, stroke, fibromyalgia, or similar nerve disorders to see how the EXOPULSE Suit affects their balance and risk of falling over time. Participants will be followed routinely, and researcher…

This observational study aims to understand how infants and toddlers develop thinking, language, movement, and social skills in the first few years of life. Researchers will assess 1,200 children aged 16 days to 42 months using standardized tests and parent questionnaires. The go…

This study is testing whether hand and arm assessments done over video calls are as good as those done in person for children with cerebral palsy. About 100 kids aged 6 to 17 will complete assessments both virtually and in a clinic, and researchers will compare the results. If vi…

This study looks at how babies' brains develop after an injury around birth. Researchers will use fun games and brain wave tests (EEG) to see if they can predict which children might have trouble with thinking and memory later. About 100 babies, both healthy and those with brain …

This study looks at how ankle-foot orthoses (AFOs) change the way leg muscles work in 30 children with cerebral palsy (ages 6–17). Researchers will measure muscle activity while children walk barefoot and with their prescribed AFO, both on a treadmill and overground. The goal is …

This study aims to understand how muscles change over time in children with spastic cerebral palsy. Researchers will use 3D ultrasound to measure muscle size, length, and quality in 229 children. The goal is to link these changes to brain injury and treatments, helping improve fu…

This registry collects information from up to 15,000 people with cerebral palsy in Switzerland, tracking their diagnosis, treatments, and outcomes over time. Researchers will use this data to study the condition and improve care. Participants must have a confirmed CP diagnosis an…

This research study follows the cognitive development of infants, both healthy and those who had a brain injury around birth. Researchers will use online games and parent questionnaires to measure attention, thinking, and language skills. The goal is to better understand how thes…

This study from the University of Calgary is testing a robotic gait trainer called the Trexo in 50 people who have trouble walking due to conditions like cerebral palsy. Researchers want to understand how different settings on the robot (like endurance vs. strength mode) affect h…

This study looks at children with spastic cerebral palsy to see if ultrasound images of their muscles can predict how well they can move. Researchers will measure muscle thickness, stiffness, and blood flow, and compare these to standard tests of motor function. The goal is to fi…

This study uses MRI scans of babies during natural sleep to understand how the brain develops in both healthy infants and those at risk for cerebral palsy. Researchers will follow about 200 infants from 3 months to 2 years old, using advanced imaging and motor skill tests. The go…

This study looks at how well people tolerate a new blended tube feed over 28 days. It includes up to 50 children and adults who need tube feeding due to conditions like cerebral palsy or cancer. Researchers will track gut symptoms and how much of the formula is taken each day.

This study looks at how children with cerebral palsy control their trunk and center of mass while walking. Researchers will measure body movements using small sensors as children walk on a special track. The goal is to better understand balance problems in these children, which c…

This study looks at whether a regular beat in music helps children with cerebral palsy and typical development learn dance moves. Researchers will teach 68 kids a short dance with and without a steady rhythm, then check how well they remember it. The goal is to understand if rhyt…

This study is working to create better methods for evaluating how children with and without stroke or cerebral palsy use their arms and hands. Researchers will observe 80 children, including those with perinatal stroke and typically developing infants, using video and play-based …

This study looks at whether a child's ability to imagine movements is connected to how well they walk, balance, and move in daily life. Researchers will test 99 children with diplegic cerebral palsy aged 5 to 18. No treatment is given; the goal is simply to understand the relatio…

This study looks at how children aged 8 to 17, both with and without cerebral palsy, use their brains to find their way around in a virtual reality game. By recording brain activity with EEG, researchers hope to understand why spatial navigation skills differ in children with CP.…

This study is testing whether a mobile health app system can help people with chronic conditions like spinal cord injury, cerebral palsy, spina bifida, or traumatic brain injury improve their self-management skills and wellness. About 160 participants will use the app for one yea…

This study looks at how the brain and spinal cord work together in people with cerebral palsy compared to those without. Researchers will use brain scans and simple tasks to measure these signals. Some participants will also receive a mild electrical current over the scalp or spi…

This study looks at how the spine and pelvis line up when children with cerebral palsy sit. Researchers will take X-rays of 100 children aged 4 to 17 who have limited walking ability. The goal is to better understand these alignments and create a standard way to take these X-rays…

This study aims to build a computer model that helps doctors predict developmental problems in babies diagnosed with brain injury, especially those at risk for cerebral palsy. Researchers will collect data from standard medical tests and ask parents to fill out two online questio…

This study follows 100 infants diagnosed with or at high risk for cerebral palsy from birth to age 2. Researchers will track changes in motor skills, speech, cognition, and more to understand how the condition naturally progresses. The goal is to gather knowledge that could impro…

This study aims to create and validate a Turkish version of a short neurological exam called the BRIEF-HINE for babies at high risk of brain problems. Researchers will test 120 infants aged 3 to 12 months who have conditions like premature birth or brain injury. The goal is to se…

This study is translating and testing a Turkish version of the Hammersmith Neonatal Neurological Examination (HNNE) for high-risk infants, such as premature babies or those with birth complications. Researchers will check if the exam is reliable and valid for use in Turkey by com…

This study follows 500 children with cerebral palsy who are having leg or spine surgery. Researchers will track their pain and opioid use for a year after surgery using surveys and sensory tests. The goal is to find out who develops chronic pain and why, so doctors can better pre…