Botox for CP kids: help or harm? new study investigates muscle changes

NCT ID NCT06991725

Recruiting now Knowledge-focused Sponsor: Universitaire Ziekenhuizen KU Leuven Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how botulinum toxin (Botox) injections change muscle structure in children with spastic cerebral palsy. Using advanced imaging like MRI and 3D ultrasound, researchers will measure muscle size, fat content, and stiffness in 51 children. The goal is to understand the balance between clinical benefits and potential muscle damage, helping guide future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Botulinum neurotoxin (Botox)
What this could lead to: If successful, this could help doctors better understand the trade-offs of using Botox in children with cerebral palsy, potentially leading to safer treatment guidelines.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly test a new therapy. Results may not change current practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebral palsy Muscle Spasticity spastic cerebral palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SPASTIC CEREBRAL PALSY (SCP)

Contacts and locations

Locations

UZ Leuven
RECRUITING

Leuven, Vlaams-Brabant, 3000, Belgium

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