Spinal zaps may quiet overactive muscles in kids with cerebral palsy

NCT ID NCT07715006

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial tests whether delivering electrical pulses to spinal nerves can temporarily calm spastic muscles in children with cerebral palsy. Researchers will stimulate the dorsal root nerves during a planned surgery and measure muscle responses. The goal is to see if this stimulation can reduce the exaggerated reflexes that cause stiffness and tightness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
electrical stimulation of the dorsal root nerves during surgery
What this could lead to
If successful, this approach could point toward a way to temporarily reduce spasticity during surgery, potentially improving outcomes for children with cerebral palsy.
What could go wrong
This is a very small, early-stage trial with only 15 children, and the stimulation is tested only during a single surgical procedure. It may not translate to lasting benefit or work outside the operating room.

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Conditions

The condition(s) this trial relates to.

cerebral palsy Muscle Spasticity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • UPMC Children's Hospital of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact Email: •••••@•••••

    Contact

    Contact

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