CEREBRAL PALSY

This study tests whether a home-use device called the Motus Nova Foot can improve walking and balance in people aged 12-20 with hemiplegia, a condition where one side of the body is weak. The device moves the ankle and foot while guiding users through video activities, and it tra…

This trial tests whether strength training combined with blood flow restriction can increase deltoid muscle thickness and improve upper limb function in children aged 4 to 6 with hemiplegic cerebral palsy. Participants will do a specially designed physical therapy program plus lo…

This trial investigates whether a robotic gait training system called Lokomat can improve standing, walking, and quality of life in children and young adults with cerebral palsy. Participants will receive 20 sessions of robot-assisted training over eight weeks, in addition to the…

This study compares two types of walking exercise—nordic walking (using poles) and treadmill training—to see which better improves walking symmetry in children aged 6-10 with unilateral cerebral palsy (weakness on one side). Both groups also receive standard physical therapy. The…

This study tests a fun, game-based training program that teaches children with cerebral palsy how to breathe better and improve their posture. The program includes exercises like blowing out candles and floating boats, along with visual and audio cues. Researchers want to see if …

This study investigates whether a program of functional progressive resistance training—exercises like sit-to-stand, step-ups, and stair climbing with gradually increasing resistance—can improve bone mineral density and balance in children with cerebral palsy. The trial includes …

This phase III trial tests whether giving tranexamic acid continuously for 24 hours after hip surgery can reduce blood loss in non-ambulatory children with cerebral palsy. About 52 children aged 4 to 16 will be randomly assigned to receive either the drug or a placebo. The goal i…

This study tests a surgical procedure to release tight muscles in the forearm of children with cerebral palsy who have a fixed elbow rotation (pronation deformity). The surgery cuts two pronator muscles to allow the arm to turn outward more easily. Researchers will measure change…

This study will test whether a gentle brain stimulation technique called tDCS, combined with task-oriented training and virtual reality, can improve movement and brain activity in 150 children with spastic cerebral palsy. Participants will be randomly assigned to receive either r…

This study tests whether a surgically implanted device that sends electrical pulses to the spinal cord can reduce spasticity (muscle stiffness) in adults with cerebral palsy. Forty participants aged 16 and older with stable, one-sided motor disability will receive the implant. Re…

This study tests whether videos recorded by parents at home can help doctors detect early signs of cerebral palsy in very preterm infants (born before 29 weeks). Researchers will compare the accuracy of family-led recordings to standard professional assessments. If successful, th…

This small study tests whether wearing a rigid leg cast (from thigh to ankle) during treadmill training can safely improve how children with cerebral palsy walk. Six children aged 7 to 14 will take part in a 4-week walking program. Researchers will use motion cameras and muscle s…

This study looks at whether a wearable garment called TheraTogs can help children and teens with cerebral palsy improve their balance and walking. Twelve participants will be tested with and without the garment to see if it makes an immediate difference. The goal is to find a sim…

This small pilot study will test whether a non-immersive virtual reality system called Rehametrics is practical and enjoyable for children with cerebral palsy aged 4 to 10. Ten participants will do balance and walking exercises using the system. The main goal is to see if kids co…

This study compares augmented reality (AR) and virtual reality (VR) during music therapy for people with cerebral palsy aged 15 to 35. Participants will use a Meta Quest 3 headset to reach for musical cubes, repeat note sequences, and play virtual instruments. The goal is to see …

This study looks at whether letting children with cerebral palsy walk sooner after calf surgery helps their foot movement and motor skills. Forty-two children aged 4 to 14 will either get a cast for 3 weeks or a brace right away, plus physical therapy. Researchers will check thei…

This study tests a non-invasive brain stimulation technique called rTMS to improve motor function in 60 children with cerebral palsy. The treatment uses magnetic pulses to enhance brain plasticity and movement recovery. Researchers will measure brain activity changes to see if th…

This trial compares two physiotherapy methods—Perception-Action Approach and Neurodevelopmental Therapy (Bobath)—for children aged 0 to 36 months with cerebral palsy or at high risk. Over 12 weeks, 24 participants will receive weekly therapy sessions and be assessed for motor fun…

This study looks at whether a combined program of 35 hours of therapy plus 15 hours of home practice works as well as 50 hours of standard therapy for improving how children aged 3 to 5 with cerebral palsy use both hands. About 66 children will take part. The goal is to make ther…

This study tests whether an intensive 15-day summer camp can improve movement and energy use in children with cerebral palsy. Thirty children aged 6 to 13 will take part in 90 hours of fun, guided exercises for their arms and legs. Researchers will measure changes in how their bo…

This study tests whether an 8-day camp that combines sensory and motor training helps children with unilateral cerebral palsy use their affected hand better than motor training alone. About 26 children aged 5 to 15 will take part. The goal is to improve hand function and daily pa…

This study compares three types of physical therapy for 90 children aged 6-12 with mild cerebral palsy: traditional therapy, active video games (exergaming), and exergaming with real-time muscle feedback. The goal is to see which approach best improves movement, balance, and moti…

This study compares carbon fiber ankle braces to standard plastic ones in 38 children with cerebral palsy aged 8-15. Each child will try both braces for 4 weeks to see which one improves walking, running, and jumping. The goal is to find out which brace helps kids be more active …

This study will test whether special 'brain gym' exercises can improve thinking abilities and quality of life in 60 children aged 6 to 8 with spastic hemiplegic cerebral palsy. The children will do these exercises along with standard physical therapy for 30 minutes, three times a…

This study tests a 6-week group bootcamp for caregivers of infants (3-15 months old) diagnosed with or at high risk for cerebral palsy. The program teaches parents how to better interact with and support their baby through physical and occupational therapy techniques. The goal is…

This study looks back at children with unilateral cerebral palsy (weakness on one side) who took part in intensive therapy programs called COLHEMI or Mini-COLHEMI. These programs provide many hours of focused hand and arm training over two weeks. Researchers want to understand ho…

This study will follow 42 children and teens with cerebral palsy who need surgery for scoliosis (a curved spine). Researchers want to see if the surgery helps them eat more and gain weight, since many have trouble eating and are underweight. The goal is to understand if the surge…

This observational study will check if breathing strength and lung function are linked to hand use in 37 children aged 6–18 with hemiparetic cerebral palsy. Participants do simple breathing tests and hand skill tasks in one clinic visit. The goal is to see if rehab programs shoul…

This study will check how well motion-capture sensors track movements in 100 children and youth with cerebral palsy while they play active video games. Researchers will compare the sensors to a gold-standard system and a therapist's assessments. The goal is to see if these sensor…