Can a simple drug cut blood loss in kids with CP after hip surgery?

NCT ID NCT07672158

Not yet recruiting Disease control Sponsor: Murdoch Childrens Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase III trial tests whether giving tranexamic acid continuously for 24 hours after hip surgery can reduce blood loss in non-ambulatory children with cerebral palsy. About 52 children aged 4 to 16 will be randomly assigned to receive either the drug or a placebo. The goal is to see if the drug lowers the need for blood transfusions and improves recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tranexamic acid
What this could lead to: If it works, this could provide a safe way to reduce blood loss and the need for blood transfusions in children with cerebral palsy after major hip surgery.
What could go wrong: This is a small, early-stage trial with only 52 children, so results may not apply to everyone. There is also a risk of seizures, which the study will monitor closely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical cerebral palsy Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD LOSS, SURGICAL CEREBRAL PALSY HIP SURGERY CORRECTIVE ORTHOPEDICS PAEDIATRICS TRANEXAMIC ACID USE

Can a simple drug cut blood loss in kids with CP after hip surgery?

Summary

What this could mean

Get notified about this study

Conditions

As listed by the trial registrant

Contacts and locations

Locations

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