Can simple play help Brain-Injured babies develop?

NCT ID NCT05130528

Completed Symptom relief Sponsor: University of Southern California Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a sensorimotor program for infants with hypoxic-ischemic encephalopathy (HIE), a brain injury from lack of oxygen at birth. Eleven babies received play-based therapy sessions in the NICU and at home for the first 6 months. The goal was to see if the program was feasible and could support development.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sensorimotor intervention (play-based therapy sessions with parents)
What this could lead to: If it works, this could point toward a simple, parent-led therapy to help babies with HIE reach developmental milestones.
What could go wrong: This was a very small feasibility study with only 11 infants, so results may not apply to all babies. The therapy is supportive, not a cure for brain injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain hypoxia - ischemia cerebral palsy perinatal asphyxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CEREBRAL PALSY HYPOXIC-ISCHEMIC ENCEPHALOPATHY

Contacts and locations

Locations

Children's Hospital Los Angeles

Los Angeles, California, 90033, United States
University of Southern California

Los Angeles, California, 90033, United States

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