New muscle relaxant drug MTR-601 tested in humans for first time
NCT ID NCT06117020
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested a new oral drug called MTR-601 in 89 healthy adults to see if it is safe and how the body processes it. The drug aims to reduce muscle stiffness and spasms, which could help people with conditions like cerebral palsy, multiple sclerosis, or stroke. Since this is a first-in-human study, it only looked at safety and dosing, not yet whether it works for those diseases.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MTR-601 (oral drug that inhibits a muscle protein to reduce spasticity)
What this could lead to
If successful, this could lead to a new treatment for muscle stiffness and spasms in conditions like cerebral palsy or multiple sclerosis.
What could go wrong
This is a very early Phase 1 trial in healthy people, not patients. It only tests safety and dosing, so it may not work for the intended conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Worldwide Clinical Trials
San Antonio, Texas, 78217, United States