Impact of Cross-Sectional design in Single-File rotary system on apical debris extrusion and postoperative pain following Single-Visit root canal treatment: an in vitro and randomized clinical study
NCT ID NCT07808684
First seen Sep 09, 2026 · Last updated Sep 09, 2026
Summary
Endodontic treatment aims to achieve optimal biological outcomes while minimizing patient's discomfort during and after the procedure. Postoperative pain remains a common complication and is considered a multifactorial phenomenon influenced by several factors, including preoperative pain, age, gender, systemic health, presence of apical periodontitis, instrumentation technique, type and design of endodontic instruments, and the use of intracanal medications.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Teeth with mature apex * Straight root canal or mild curvature not exceeding(5-10) Schneider. * Has intact crown ( coronal structure) * Presence of one orifices and one apices, patency achieved by a #10-15 K-file to the apical foramen Exclusion Criteria: * Previous root canal treatment. * Internal/external resorption. * Immature root apices. * Caries/cracks/fractures on the root surface. * Root canal curvature more than 10 degrees. * Teeth in which the apical minor constriction was gauged larger than a size 20 hand file.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Endodontics, Faculty of Dentistry, Minia University
RECRUITINGMinya, Minya Governorate, Egypt
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