Could vitamin d boost chemo success in breast cancer?

NCT ID NCT04677816

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking vitamin D supplements during standard chemotherapy can help more tumors disappear in people with triple-negative breast cancer who are low in vitamin D. About 50 participants will receive vitamin D plus chemotherapy, and researchers will compare their response to historical data. The goal is to see if correcting vitamin D deficiency improves the chance of a complete response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Vitamin D

What this could lead to

If it works, this could show that correcting vitamin D deficiency helps chemotherapy work better for triple-negative breast cancer.

What could go wrong

This is a small early-phase study with only 50 participants, so results may not apply broadly. Vitamin D may not improve outcomes, and standard chemotherapy side effects still apply.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

invasive breast carcinoma triple-negative breast carcinoma vitamin D deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wake Forest Baptist Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact

    Contact