Timing of extra nutrition could save lives in ICU

NCT ID NCT07085455

Recruiting now Disease control Sponsor: Dong Zhang Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether starting extra nutrition through an IV earlier (on day 4) versus later (on day 8) helps critically ill patients survive. About 946 adults with organ failure who cannot get enough nutrition from a feeding tube will be randomly assigned to one of the two timing groups. The main goal is to see if early IV nutrition lowers the chance of death within 28 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: supplemental parenteral nutrition (IV nutrition)
What this could lead to: If early IV nutrition works, it could reduce deaths and improve recovery in critically ill patients who cannot get enough nutrition through a feeding tube.
What could go wrong: This is a mid-stage trial, so results may not be definitive. Early IV nutrition might cause side effects like infections or liver problems, and the benefit may be small or absent.

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Conditions

The condition(s) this trial relates to.

Critical Illness nutritional deficiency disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS ENTERAL NUTRITION INTOLERANCE INADEQUATE NUTRITIONAL INTAKE ORGAN DYSFUNCTION

Contacts and locations

Locations

The First Hospital of Jilin University
NOT_YET_RECRUITING

Changchun, Jilin, 130021, China
The First Hospital of Jilin University
RECRUITING

Changchun, Jilin, 130021, China

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