Could a simple supplement shrink fibroids and prevent surgery?
NCT ID NCT05448365
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether a daily supplement containing vitamin D, EGCG (from green tea), D-chiro-inositol, and vitamin B6 can shrink uterine fibroids in women who are eligible for surgery. Sixty women will take either the supplement or a placebo for three months. The main goal is to see if the fibroids get smaller and if fewer women end up needing surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
combination of vitamin D, epigallocatechin gallate (EGCG), D-chiro-inositol, and vitamin B6
What this could lead to
If it works, this could offer a natural supplement option to shrink fibroids and help some women avoid surgery.
What could go wrong
This is a small early-phase trial with only 60 participants and no phase designation, so results may not be conclusive. The supplement may not shrink fibroids enough to make a real difference.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ospedale Dario camberlingo
RECRUITINGFrancavilla Fontana, Apulia, 72021, Italy
Contact Email: •••••@•••••
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Ospedale Veris Delli Ponti
NOT_YET_RECRUITINGScorrano, Apulia, 73020, Italy
Contact Email: •••••@•••••