Sugar-Alcohol combo may restore periods in PCOS

NCT ID NCT07701525

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This phase 4 trial tests whether a daily combination of myo-inositol and D-chiro-inositol (with folic acid) can improve menstrual regularity and hormone levels in women with polycystic ovary syndrome (PCOS). Sixty women aged 18–45 with PCOS will receive either the inositol combination or a placebo (folic acid alone) for three months. Researchers will track changes in cycle length, bleeding, and blood levels of LH, FSH, and testosterone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a combination of myo-inositol and D-chiro-inositol (with folic acid)
What this could lead to
If effective, this combination could offer a simple, non-hormonal option to help regulate periods and improve hormone balance in women with PCOS.
What could go wrong
This is a small, short-term trial (60 women, 3 months), so results may not apply to all PCOS patients. The supplement may not outperform folic acid alone.

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Conditions

The condition(s) this trial relates to.

amenorrhea Hyperandrogenism Menorrhagia Menstruation Disturbances Oligomenorrhea polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nishtar Medical University and Hospital Multan

    Multan, Punjab Province, 60000, Pakistan

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