Could taking two prenatal supplements at once be just as good?

NCT ID NCT06568315

Recruiting now Disease control Sponsor: Johns Hopkins Bloomberg School of Public Health Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 11, 2026 · Updated 4 times

Summary

This study in Burkina Faso and Pakistan will enroll 3,200 pregnant women to see if taking daily calcium and iron-containing multiple micronutrient supplements together is as effective as taking them at different times. The goal is to simplify supplement routines without harming the mother's or baby's iron levels. Participants will be randomly assigned to one of two schedules and provide blood samples throughout pregnancy and at birth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: multiple micronutrient supplement (including iron) and calcium supplement
What this could lead to: If it works, this could simplify prenatal supplement routines and improve adherence, potentially reducing anemia in pregnant women and newborns.
What could go wrong: This is a large Phase 3 trial, but it only tests non-inferiority—meaning it aims to show that taking supplements together is not worse than separately. It may still find reduced iron absorption, and results may not apply to all populations.

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Conditions

The condition(s) this trial relates to.

anemia iron deficiency anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEMIA, IRON DEFICIENCY

Contacts and locations

Locations

Aga Khan University
RECRUITING

Karachi, Pakistan
Institut Africain de Santé Publique (African Institute of Public Health)
RECRUITING

Ouagadougou, Burkina Faso

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