Can a vitamin B3 pill help older veterans stay stronger longer?
NCT ID NCT04691986
First seen Nov 01, 2025
Summary
This study tests whether nicotinamide riboside (NR), a form of vitamin B3, can improve muscle strength, endurance, and walking speed in older veterans aged 65-85. Participants take NR or a placebo daily for several weeks and undergo exercise tests and muscle biopsies. The goal is to see if boosting NAD+ levels can slow age-related muscle decline and frailty.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Kansas City VA Medical Center, Kansas City, MO
Kansas City, Missouri, 64128-2226, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nicotinamide riboside (a form of vitamin B3)
What this could lead to
If it works, this could point toward a simple nutritional supplement to help older adults maintain muscle strength and mobility.
What could go wrong
This is a small, early-stage trial with 74 participants, so results may not apply broadly. The supplement may not improve physical function beyond a placebo effect.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.