Can a nutrient cocktail during dialysis save muscle?
NCT ID NCT04094038
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving a special nutrient mixture (Olimel N12) during hemodialysis can help prevent muscle loss and improve quality of life in people with end-stage kidney disease. About 166 patients will receive either the nutrient infusion or a simple glucose solution during their regular dialysis sessions. The main goal is to see if lean tissue mass changes over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Olimel N12 (a mixture of glucose, lipids, and amino acids given intravenously during dialysis)
- What this could lead to
- If it works, this could provide a way to prevent muscle loss and improve quality of life for people on long-term hemodialysis.
- What could go wrong
- This is a phase 4 study, but previous evidence for this approach is weak. The benefit may be small or not apply to all patients, and there are risks like infection or allergic reactions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Erasmus MC
Rotterdam, Netherlands
-
Franciscus Gasthuis & Vlietland
Rotterdam, Netherlands
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