SARCOPENIA

This study is testing if a new, gentler daily dialysis schedule can help patients with advanced kidney failure complete a rehabilitation program. The program combines physical exercise and nutrition support. Researchers want to see if this approach helps patients regain muscle st…

This study aims to see if the type of anesthesia used during colorectal cancer surgery affects how much muscle mass patients lose afterward. Researchers will compare two common anesthesia methods in 40 patients to determine which one better preserves muscle strength and size. The…

This study is testing whether a daily supplement made from fruit and vegetable compounds (polyphenols) can make exercise more effective for improving strength and physical function in adults over 60. For 12 weeks, 40 participants will follow a supervised exercise program while ta…

This study is testing whether adding electrical muscle stimulation (EMS) to leg exercises is better than regular exercise alone for improving muscle strength, body composition, and artery health in postmenopausal women. Researchers will compare three groups: one doing EMS with ex…

This study is testing whether a short, home-based program of exercise and high-protein nutrition is safe and practical for patients to do in the two weeks before head or neck cancer surgery. Researchers want to see if patients can complete the program and if it causes any problem…

This study is testing a new type of clinic designed to diagnose and treat muscle loss (sarcopenia) in people with COPD. The clinic brings together a team of specialists to create a treatment plan. Researchers want to see if this approach helps patients gain muscle, get stronger, …

This study is testing whether a digital exercise therapy device is better than doing exercises on your own for improving muscle strength in older adults with sarcopenia, a condition of age-related muscle loss. About 130 participants will be randomly assigned to either use the dig…

This study is testing whether taking a creatine supplement daily for 12 weeks can help older adults with sarcopenia, a condition of age-related muscle loss. Researchers will measure if it improves handgrip strength, body composition, physical fitness, and even brain function. The…

This study is testing a new, fun group exercise program designed to help older adults stay physically and mentally capable. It will compare the new program to a standard exercise routine over 14 weeks. Researchers want to see if the enjoyable, social format helps people stick wit…

This study is for people with advanced liver disease (cirrhosis) who have lost significant muscle mass (sarcopenia) and need a standard procedure called TIPS to treat internal bleeding or fluid buildup. Researchers want to see if adding a specific nutritional supplement (branched…

This study is testing a new, portable device that uses a sticker-like sensor to measure muscle signals. The goal is to create a better, easier way to diagnose sarcopenia, which is age-related muscle loss that leads to weakness and loss of independence. Researchers will enroll 846…

This study aims to see if measuring calf circumference with a simple tape measure is as good as a specialized X-ray scan for diagnosing sarcopenia (serious muscle loss) in hospitalized people aged 75 and older. Researchers will compare the two methods in 298 participants to check…

This study is testing whether a 12-week smartphone program can help older adults at risk of muscle loss (sarcopenia) stay strong and independent. Sixty participants will either use a special app with exercise videos, nutrition tips, and daily reminders, or receive standard clinic…

This study aims to see which type of exercise is better for rebuilding muscle and improving function in people recovering from a stroke. It will compare short bursts of high-intensity exercise (HIIT) with longer sessions of moderate, steady exercise. Researchers will measure musc…

This study aims to find out if a supervised exercise program that includes relaxation techniques is better than doing exercises at home alone for breast cancer survivors. It focuses on helping people regain muscle mass and strength lost during cancer treatment and improving their…

This study is testing if a 12-week exercise program done during dialysis sessions can help patients with chronic kidney disease. Researchers want to see if supervised strength and aerobic workouts improve muscle mass, strength, sleep quality, and overall quality of life. About 58…

This study aims to see if adding specific exercises to standard physical therapy helps people with Parkinson's disease who also have significant muscle loss (sarcopenia). Researchers will compare standard rehab alone to rehab plus either resistance band training or treadmill walk…

This study is testing whether adding electroacupuncture to standard rehabilitation training can better improve walking ability in older adults with sarcopenia, a condition of age-related muscle loss and weakness. It will enroll 120 participants who will either receive rehab train…

This study is testing whether a nutritional supplement called nicotinamide riboside (a form of vitamin B3) can help improve strength, walking speed, and overall physical function in older veterans. Researchers will enroll 144 healthy adults aged 65-85 to take either the supplemen…

This study is testing if showing older adults with age-related muscle loss the speed of their leg exercises in real-time helps them perform better and feel more motivated than just doing the exercises without that feedback. Researchers will compare two groups over three weekly se…

This is a small, early-stage study to see if a special exercise program can help children with acute lymphoblastic leukemia (ALL) who are showing early signs of muscle weakness and frailty from their treatment. Researchers will enroll 60 children aged 5-17 and randomly assign tho…

This study is testing whether a 12-week program of resistance exercises and essential amino acid supplements can help improve muscle mass and strength in people receiving hemodialysis who have sarcopenia (muscle loss). The researchers want to see if this combined approach can mak…

This study is testing whether a powder made from silkworm pupae can improve the nutritional status, muscle strength, and quality of life for people with Alzheimer's disease. Researchers will give 200 participants either the silkworm powder or a placebo daily for three months to s…

This study aims to better understand muscle loss (sarcopenia) in people with heart failure using two special types of MRI scans. Researchers will scan 70 participants—some with heart failure and muscle loss, some with heart failure without muscle loss, and some healthy volunteers…

This large observational study aims to understand how age-related muscle loss (sarcopenia) interacts with metabolic diseases like diabetes to accelerate aging and increase risks of heart problems and death. Researchers will follow 10,000 adults over time, collecting health data, …

This study aims to understand if having low muscle mass at diagnosis is linked to experiencing more severe side effects from chemotherapy. It will follow 300 older adults newly diagnosed with advanced colorectal cancer who are starting standard chemotherapy. The goal is to gather…

This study aims to understand how common malnutrition and age-related muscle loss (sarcopenia) are among adults visiting outpatient clinics in Turkey. Researchers will screen 7,500 participants aged 18 and over using questionnaires and simple physical measurements. The study is o…

This study aims to understand how and why critically ill patients lose muscle mass, a condition linked to frailty and poor recovery. Researchers will observe 250 adults in intensive care to identify factors that might be changed to help patients get stronger. The goal is to gathe…

This study aims to check the accuracy and consistency of various laboratory tests and research procedures used to study chronic diseases like obesity, diabetes, and heart failure. It will enroll up to 100 adults, both healthy and with certain conditions, to perform tests multiple…

This study aims to see if brief, simple tests measuring muscle strength, breathing, walking, and memory can predict which older adults (age 65+) are more likely to have complications after major abdominal surgery. Researchers will perform these tests during routine pre-surgery vi…

This study aims to understand if a patient's body composition, specifically muscle mass, affects how much chemotherapy they receive and their risk of severe side effects. Researchers will observe 132 adults with advanced non-small cell lung cancer who are starting standard chemot…

This study aims to understand whether muscle loss (called sarcopenia) occurs in women with gestational diabetes during pregnancy. Researchers will measure muscle mass and strength in 200 pregnant women to see if this condition affects pregnancy outcomes or cognitive function. The…

This study aims to understand if age-related muscle loss, called sarcopenia, is linked to specific patterns of rotator cuff tears. Researchers will enroll 104 adults with chronic shoulder pain and a rotator cuff syndrome diagnosis. They will measure participants' muscle strength …

This study aims to understand how chronic diseases like high blood pressure, diabetes, and frailty develop and progress in a rural Chinese county. Researchers will follow 20,000 adult residents for three years, collecting health data and samples to build a detailed picture of com…

This study aims to understand how breast cancer treatment affects body composition over time. Researchers will follow 100 patients for 2 years after surgery and therapy to track muscle loss, fat changes, and physical function. The goal is to gather detailed information about the …

This study aims to understand if muscle loss (sarcopenia) changes how patients respond to muscle-relaxing drugs used during anesthesia for gastrointestinal cancer surgery. Researchers will observe 100 patients during their operations, comparing those with and without muscle loss.…

This study aims to understand how a standard liver procedure (TIPS) might help improve severe muscle loss (sarcopenia) in people with advanced liver cirrhosis. Researchers will follow 132 patients after their TIPS surgery, measuring a specific protein (FGF21) in their blood and t…

This study aims to understand how a patient's nutritional status and body composition affect their treatment outcomes for Crohn's disease and ulcerative colitis. Researchers will observe 300 patients starting new medications or having surgery, measuring things like muscle mass an…

This small pilot study is exploring whether combining electrical muscle stimulation with light exercise can help older adults activate their muscles more effectively, as this ability often declines with age. Researchers will test if this approach improves measures of strength, ba…

This study aims to understand the connection between gut bacteria and sarcopenia, the age-related loss of muscle mass and strength. Researchers will compare the gut bacteria of older adults with and without sarcopenia to younger adults. The goal is to gather information that coul…

This study aims to understand how a person's diet, particularly its inflammatory potential, and the bacteria in their gut might be connected to sarcopenia, which is age-related muscle loss. Researchers will collect information from 1,220 adults aged 60 and older about their diets…

This study aims to understand how common muscle weakness and cognitive problems (often called 'chemobrain') are in people who have finished cancer treatment. Researchers will collect health data from 100 adult cancer survivors during a standard follow-up check-up day. The goal is…

This study aims to find out how many people with stomach or intestinal cancers show early warning signs of muscle loss, known as sarcopenia. Researchers will screen 60 patients using a simple questionnaire before they start cancer treatment and again during treatment. Patients wh…