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Home workouts and sound waves: a new strategy to fight Age-Related muscle loss

NCT ID NCT07692308

Disease control Sponsor: I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 14, 2026 · Updated 3 times

Summary

This study tests a 48-week home-based exercise program (resistance and aerobic training) delivered via a digital platform for people over 50 with or at risk of sarcopenia—age-related muscle loss. It also evaluates a new ultrasound method to detect early muscle changes. The goal is to see if the exercise program improves leg strength and if the ultrasound can reliably spot muscle decline early.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
digitally delivered home-based exercise program (resistance and aerobic training)
What this could lead to
If successful, this approach could provide a simple, scalable way to detect sarcopenia early and slow muscle decline with home exercise, helping older adults stay independent longer.
What could go wrong
This is a mid-sized trial testing a behavioral intervention, not a drug. Results may vary, and long-term adherence to home exercise can be challenging. The ultrasound method is still experimental.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 192 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Sedentary individuals aged over 50 years. * Individuals with sarcopenia, defined as reduced muscle mass assessed by bioelectrical impedance analysis and reduced muscle strength assessed by handgrip strength, according to EWGSOP2 criteria. * Individuals at risk of sarcopenia, defined as reduced muscle mass with preserved muscle strength. * Healthy age-, sex-, and physical activity-matched older adults eligible for inclusion in the reference cohort. * Ability to understand the study procedures and provide written informed consent. Exclusion Criteria: * Hospitalization within the previous 6 weeks. * Substance or alcohol abuse. * Use of medications that may impair balance or coordination. * Major locomotor impairments. * Inability to complete the exercise protocol. * Medical, cognitive, or functional conditions that, in the opinion of the investigators, may interfere with safe participation, adherence to the study procedures, or completion of the follow-up assessments.

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sarcopenia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • IRCCS Ospedale Galeazzi-Sant'Ambrogio

    RECRUITING

    Milan, Mi, 20157, Italy

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