Can a steroid help seniors regain muscle? new trial investigates

NCT ID NCT05978206

Recruiting now Disease control Sponsor: National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a drug called nandrolone decanoate, combined with a structured exercise and diet program, can improve strength and mobility in older adults with sarcopenia (age-related muscle loss). About 168 people aged 60–99 will receive either the drug or a placebo, plus the same exercise and diet plan, for 12 weeks. Researchers will measure changes in walking speed, chair-stand time, and overall physical function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nandrolone decanoate (an anabolic steroid)
What this could lead to: If it works, this could point toward a treatment for sarcopenia that combines medication, exercise, and diet to help older adults regain strength and mobility.
What could go wrong: This is an early Phase 2 trial with only 168 people, so results may not apply to everyone. The steroid may cause side effects like hormonal changes or liver issues, and the benefit over exercise and diet alone is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARCOPENIA

Contacts and locations

Locations

Centrum Wsparcia Badań Klinicznych
RECRUITING

Warsaw, Masovian Voivodeship, 02-637, Poland

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