10,000 volunteers join hunt for Aging's hidden clues

NCT ID NCT07205510

Recruiting now Knowledge-focused Sponsor: RenJi Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The SMILE study is tracking 10,000 adults aged 18 and older to see how sarcopenia (age-related muscle loss) and metabolic diseases like diabetes influence overall health and lifespan. Researchers will collect data from medical records, tests, and surveys over time. This is an observational study, meaning no treatment is given—it aims to uncover patterns that could guide future care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal key links between muscle loss, metabolic diseases, and aging, pointing toward better prevention or early intervention strategies.
What could go wrong: This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may take years to emerge.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

metabolic disease Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING ALL-CAUSE MORTALITY CARDIOMETABOLIC DISEASES METABOLIC DISEASES SARCOPENIA

Contacts and locations

Locations

Department of Geriatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
RECRUITING

Shanghai, China

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