Renji Hospital

This study is testing how well the drug dalpiciclib works to control advanced breast cancer that is hormone receptor-positive and HER2-negative. Researchers will follow 103 patients in real-world settings to see how long the drug keeps the cancer from worsening and monitor any si…

This study compares two new access methods for removing blood clots from leg veins against the traditional approach. Researchers want to see if accessing the clot through different entry points can prevent long-term complications as effectively as when treating simpler cases. The…

This study aims to understand if receiving therapy before breast cancer surgery improves treatment response and long-term survival. It will enroll 488 women with early or advanced breast cancer who plan to get pre-operative treatment. Researchers will compare different treatment …

This study is testing whether washing the brain's fluid-filled spaces with a saline solution can help people with a severe brain infection called ventriculitis. Researchers will compare this surgical technique to standard antibiotic treatment in 310 adults to see if it leads to b…

This study is comparing two different ways of giving a breast cancer drug called pyrotinib to see which is better at keeping the cancer from coming back. It involves nearly 500 people with a specific type of breast cancer (HER2-positive) who have already finished their initial tr…

This study is testing if a long-term, supervised exercise program can help people with pulmonary arterial hypertension (PAH). PAH is a serious lung and heart condition that makes people very short of breath. Researchers want to see if one year of specific aerobic and breathing ex…

This large study is testing if a drug called tranexamic acid (TXA) can safely reduce dangerous blood loss during liver transplant surgery. Over 1500 adult patients receiving a transplant will be randomly given either TXA or a placebo (saltwater) during their operation. The main g…

This study observes how well the drug Disitamab vedotin (RC48-ADC) works and what side effects it causes for people with breast cancer in real-world settings. It will follow 45 patients who are already taking or have taken this medication. The main goal is to see how long patient…

This study is testing whether adding a drug called pyrotinib to the standard one-year treatment (trastuzumab) helps prevent breast cancer from returning in women who still have cancer cells after initial chemotherapy and targeted therapy. It involves about 316 women with a specif…

This study is testing a new idea to help people with heart failure. Researchers want to see if gently pacing the main breathing muscle (the diaphragm) can improve how well the heart pumps. They will test this in 10 patients who are already scheduled to get a special heart device,…

This study is testing a protective filter device used during procedures to clear blocked leg arteries. The filter is designed to catch any debris or clots that break loose during the procedure, preventing them from traveling further down the leg and causing new blockages. Researc…

This study is testing whether giving two drugs before surgery can help control high-risk cancer in the upper urinary tract while preserving kidney function. About 20 patients who have this specific cancer and want to avoid complete kidney removal will receive the drug combination…

This study is testing whether the drug RC48-ADC can help control advanced breast cancer that has low levels of the HER2 protein. It's for patients who have already tried up to one chemotherapy treatment for their advanced cancer but haven't used this type of drug before. Research…

This study is observing 3000 patients in China with Primary Biliary Cholangitis (PBC), a chronic liver disease. Researchers want to see if patients who have a better response to standard medication, shown by improved liver blood tests, live longer without serious complications li…

This study is testing whether a combination of three drugs (adebrelimab, etoposide, and cisplatin) given before bladder removal surgery can help shrink or eliminate a rare and aggressive form of bladder cancer called neuroendocrine carcinoma. About 22 patients with this specific …

This study is testing two new imaging agents for PET/CT scans to see if they can better detect and characterize breast cancer tumors. The goal is to see if these new scans can more accurately show where cancer is located and how much of certain proteins the tumors have. This coul…

This study is testing new radioactive tracer chemicals for PET/CT scans to see if they can better detect and monitor cancers of the digestive system, including stomach, colon, liver, and pancreatic cancer. About 400 adults with confirmed or suspected digestive cancer will receive…

This study is testing whether tiny traces of cancer DNA found in blood and urine can predict if cancer will come back after surgery for upper urinary tract cancer. Researchers will follow 84 patients after their surgery and chemotherapy/immunotherapy, collecting samples over two …

This study is testing a new type of imaging scan to see if it can better detect and monitor many different solid tumors. The scan uses a special tracer that attaches to a protein called Trop2, which is often found on cancer cells. Researchers will compare this new scan to standar…

This study is testing a new type of PET/CT scan that uses a special tracer called [18F]RCCB6. The goal is to see if this scan can more accurately detect and diagnose kidney cancer, especially a common type called clear cell renal cell carcinoma. Researchers will enroll 300 partic…

This study is testing new types of PET scans to see if they can help doctors better understand pancreatic cancer. The scans use special tracers to highlight specific targets on cancer cells. The goal is to see if these scans can predict which patients are most likely to benefit f…

This study is testing whether a special blood test that looks for stray cancer cells can help predict if breast cancer might come back after surgery and chemotherapy. Researchers will follow 484 women who have already completed their main breast cancer treatments to see if the te…

This study aims to understand a rare but serious complication where patients develop acute pancreatitis (inflammation of the pancreas) after a procedure to remove blood clots. Researchers will look back at medical records to see how often this happens, identify which patients or …

This study aims to understand the complex links between age-related muscle loss (sarcopenia), conditions like diabetes and heart disease, and the overall aging process. Researchers will follow 10,000 adults over time, collecting health data to see how these factors interact and a…

This study aims to find out which of two common brain surgeries works better for patients with a dangerous type of bleeding on the brain's surface. Researchers will follow 2,000 patients in China who need surgery for this condition. They will compare outcomes like recovery, compl…

This study aims to understand why kidney problems develop in some people after a liver transplant. Researchers will follow 369 patients who already have signs of kidney damage and have had a kidney biopsy. Over two years, they will track how kidney health changes and try to ident…

This study aims to understand if a minimally invasive heart valve replacement procedure (TAVI) can help reverse scarring and structural changes in the heart muscle of patients with severe aortic stenosis. Researchers will use a special type of PET scan to measure heart scarring b…