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Blood test may spot prostate cancer without a needle

NCT ID NCT07755592

Recruiting now Diagnosis Sponsor: RenJi Hospital Source: ClinicalTrials.gov ↗

First seen Aug 10, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This trial is testing a new blood test that measures tiny molecules called microRNAs to help doctors tell the difference between prostate cancer and benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate. The study will include 500 men who are scheduled for a prostate biopsy due to suspicious findings. The test's accuracy will be compared to the standard PSA blood test, using biopsy results as the gold standard. If it works well, this could spare many men from unnecessary invasive biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A blood test that measures a panel of microRNAs (miRNAs) in serum to help tell prostate cancer from benign prostatic hyperplasia.
What this could lead to
If successful, this blood test could offer a more accurate, non-invasive way to detect prostate cancer, potentially reducing unnecessary biopsies and improving early diagnosis.
What could go wrong
The test is still being validated and may not prove accurate enough in practice. It is a single-center study, and results need confirmation in larger, more diverse populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

disease prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER (DIAGNOSIS)

Contacts and locations

Locations

  • Renji Hospital Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, 200127, China

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