Extra numbing shot may ease pain of prostate biopsy

NCT ID NCT07683182

Ongoing Symptom relief Sponsor: Marmara University Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests whether adding an extra numbing injection inside the prostate can reduce pain during a prostate biopsy. Fifty men undergoing the procedure will receive either standard numbing of the skin or the standard plus the extra injection. Pain levels are measured before, during, and after the biopsy using a simple 0-to-10 scale. The goal is to find a better way to keep patients comfortable during this common cancer-screening procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Prilocaine and bupivacaine (local anesthetics)
What this could lead to: If effective, this technique could make prostate biopsy less painful and more tolerable for patients.
What could go wrong: This is a small, early-stage study with only 50 participants, so results may not apply to all patients. Adding extra anesthesia could also carry its own risks, such as discomfort or rare side effects.

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Conditions

The condition(s) this trial relates to.

disease prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER (DIAGNOSIS) PROSTATE-SPECIFIC ANTIGEN

Contacts and locations

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Locations

Marmara University School of Medicine

Istanbul, Pendik, 34722, Turkey (Türkiye)

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