A sharper eye on prostate cancer return: PSMA PET vs. MRI
NCT ID NCT07766122
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This pilot study investigates whether a PSMA PET scan, using an injected radiotracer, can detect clinically significant prostate cancer recurrence one year after focal HIFU treatment, compared with the standard MRI. About 30 men with prostate cancer who meet specific criteria will undergo both imaging tests, followed by a prostate biopsy as the gold standard to confirm any recurrence. The goal is to see if PSMA PET is as accurate as MRI in spotting cancer that has come back, which could improve monitoring after focal therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PSMA PET scan with an injected radiotracer
- What this could lead to
- If PSMA PET proves as accurate as MRI, it could offer a more reliable way to detect prostate cancer recurrence after focal therapy, potentially guiding earlier and more precise follow-up care.
- What could go wrong
- This is a small pilot study, so results may not be conclusive. PSMA PET might not match MRI's accuracy, and the radiotracer injection carries minor risks like allergic reactions or radiation exposure.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital of Toulouse
Toulouse, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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