University Hospital, Toulouse

This study is testing whether injections of a patient's own processed fat cells can help heal stubborn, painful finger ulcers caused by scleroderma. It will compare the cell injections to a placebo in 32 adults with systemic sclerosis who have ulcers that haven't healed with stan…

This early-stage study is testing whether injections of donor stem cells can help heal painful fistulas (abnormal tunnels) in people with Crohn's disease. The trial is for patients whose fistulas haven't improved with standard surgery and medication. Researchers will test two dif…

This study is testing whether measuring specific, fast brain signals called 'fast-ripples' can help doctors better plan surgery for people with drug-resistant epilepsy. It will compare surgery outcomes for 440 patients, where half have their brain surgery plan informed by these s…

This study aims to find the safest way to switch from one osteoporosis medication (denosumab) to another (zoledronic acid) in postmenopausal women. Stopping denosumab can sometimes cause rapid bone loss and increase fracture risk. Researchers will compare two approaches: a standa…

This study is testing whether a monthly monitoring program can help older adults with multiple myeloma maintain their independence. The program checks six key areas of health like mobility and memory to catch problems early. Researchers want to see if patients can stick with the …

This study is testing if placing a temporary balloon in the stomach, combined with diet and exercise, helps obese adults with uncontrolled asthma breathe better. Researchers will compare this approach to diet and exercise alone. The main goal is to see if more people using the ba…

This study is testing whether changing the timing of a common fertility treatment can help more people have babies. Researchers want to see if waiting 42 hours instead of 36 hours after an ovulation trigger shot improves live birth rates during intrauterine insemination (IUI). Th…

This study is testing a new bedside device called Quantra to help doctors better manage bleeding during liver transplant surgery. It compares the new device's guidance for blood transfusions against the standard approach. The goal is to see if using Quantra can reduce the amount …

This study is testing a new type of PET scan to see if it can better detect and characterize endometriosis lesions compared to a standard MRI. Researchers will enroll 20 people with endometriosis who are scheduled for surgery. The main goal is to see if the scan results can be li…

This study is testing if using a portable lung ultrasound machine during emergency calls for severe breathing trouble helps doctors make a more accurate diagnosis and choose the right treatment faster. It involves 40 adult patients with severe shortness of breath who are treated …

This study aims to see if measuring a substance called D-lactate in spinal fluid can help doctors diagnose meningitis (a serious brain infection) in patients who have a temporary brain drain (ventriculostomy) after neurosurgery. Researchers will enroll 185 patients at Toulouse Un…

This study aims to see if testing hair samples can accurately tell if someone with HIV is taking their medication as prescribed. Researchers will analyze small segments of hair from 30 patients over six months to measure drug levels. The goal is to develop a less invasive, more r…

This study is testing if using a bedside ultrasound machine can help emergency doctors quickly and correctly figure out what's causing sudden, severe shortness of breath in people over 65. Researchers will compare the usual care to a new approach where doctors use ultrasound on t…

This study is testing whether a 6-month personalized exercise program can help children and teenagers with Marfan syndrome build endurance and improve their quality of life. Researchers will work with 30 young patients to create physical activities that fit into their daily routi…

This study is testing if a short, guided breathing exercise called 'cardiac coherence' can help reduce anxiety for people who feel nervous about getting an MRI scan. The researchers will enroll 60 adults who report high anxiety about their upcoming upper-body MRI. They will measu…

This study is testing whether a structured, supervised exercise program helps women feel better and reduces healthcare costs while they are actively receiving treatment for breast cancer. Researchers will compare the exercise program to just giving general advice about staying ac…

This study tests if a single educational session can help people with stable Crohn's disease or ulcerative colitis stick with a recommended exercise program. Researchers want to see if learning about the benefits of safe, adapted physical activity makes patients more likely to ex…

This study is testing if a precise, ultrasound-guided steroid injection into the knee can quickly relieve pain from a worn or torn meniscus (a common knee cartilage injury). 152 adults with ongoing knee pain will receive either the real steroid injection or a placebo (saltwater) …

This study aims to understand how the brain ages by looking for early signs of future memory changes. Researchers will use MRI brain scans and eye-tracking tests on 100 healthy volunteers over 60 years old to see if certain measurements can predict who stays sharp and who might d…

This study aims to understand if practicing dance to a regular rhythm helps children with cerebral palsy or other motor disorders learn movement sequences better. Researchers will compare how 68 children, both with and without motor disorders, learn a dance choreography with and …

This study aims to better understand rare eye malformations that occur during early development. Researchers will create 3D 'mini-eye' models in the lab using stem cells donated by 20 patients with these conditions. By studying these models, they hope to learn how these eye defec…

This study aims to collect blood and other fluid samples from 3000 people with lung nodules or lung cancer. The goal is to find biological markers that could help doctors diagnose cancer earlier, predict how it will progress, and choose the best treatments. Researchers will compa…

This study aims to build a collection of blood samples and medical information from 800 patients with autoimmune skin diseases like psoriasis, lupus, and eczema. Researchers will analyze these samples to identify biological markers and understand how these diseases develop. The g…

This study aims to understand why kidney disease happens, gets worse, or leads to complications like infections or heart problems. Researchers will follow 5,000 adult patients with or at risk for kidney disease for 10 years, collecting blood and urine samples. They will analyze t…

This study aims to test a new scoring system (the IFEED score) to better define and measure a common complication called postoperative ileus, where the bowels temporarily stop working after digestive surgery. Researchers will follow 161 patients undergoing colorectal surgery to s…

This study aims to understand the full medical journey and costs for patients who need major facial reconstruction after head and neck cancer surgery. It will follow 200 patients in France for a year, tracking their hospital visits, treatments, medications, and quality of life. T…

This study aims to build a collection of blood and spinal fluid samples from 1,000 patients with rare neurological diseases where the immune system may be attacking the nervous system. Researchers will analyze these samples to discover new biological markers that could help with …

This study aims to create a collection of blood and urine samples from people with Noonan syndrome. The goal is to help researchers better understand how the disease works and find biological signs that might predict how severe it could become. The samples will be used for future…

This study is testing whether a substance in urine (called S1P) can serve as a simple marker for overactive bladder in people with multiple sclerosis (MS). Currently, diagnosing and monitoring this common MS symptom requires an invasive and uncomfortable test. Researchers will en…

This study aims to discover blood markers that could help predict whether a person's type 2 diabetes will go into remission after weight loss surgery. Researchers will collect blood, muscle, and fat tissue samples from 50 obese patients with type 2 diabetes who are scheduled for …

This study aims to collect blood and urine samples from 300 people with Marfan syndrome or related conditions. The samples will be stored for future research to better understand how the disease progresses and what factors might predict its severity. Participants will provide ext…

This study aims to collect and store blood, urine, stool, saliva, and tumor samples from 500 bladder cancer patients at Toulouse University Hospital. Researchers want to understand how bacteria in the bladder and gut might affect how patients respond to cancer treatments like BCG…

This study aims to understand the biological differences between inherited lymphedema and lymphedema that develops after cancer surgery. Researchers will compare tissue samples from 60 adults with either type of lymphedema to their own healthy tissue. The goal is to identify spec…

This study aims to understand if people with a specific sleep disorder (idiopathic REM Sleep Behavior Disorder, or iRBD) experience pain differently. iRBD is a known early risk factor for developing Parkinson's disease. Researchers will compare pain levels and characteristics in …

This study aims to find a way to objectively measure 'internal tremors'—a shaking sensation some Parkinson's patients feel inside that isn't visible. Researchers will use motion sensors on 60 people (both Parkinson's patients and healthy volunteers) to see if they can detect a sp…

This study aims to understand how children remember and emotionally cope with Guillain-Barré Syndrome (GBS) years after their recovery. Researchers will interview 25 French children aged 10+ who had GBS 2-5 years ago about their illness experience and current feelings. The goal i…

This study aims to create a large collection of blood samples and health information from people with autoimmune diseases like lupus and scleroderma. Researchers will use these samples to look for new biological markers that could help diagnose diseases earlier, predict how they …

This study is creating a national registry to track 1500 adult patients in France who have immune thrombocytopenia (ITP) or autoimmune hemolytic anemia (AIHA). The goal is to understand how these rare blood disorders progress in real life and see how well current treatments work …

This study aims to understand how body composition, specifically lean muscle mass, affects how the antiviral drug acyclovir is processed and eliminated by the kidneys in people with different body weights. Researchers will measure drug levels in the blood and urine of 20 healthy …