Stem cell shots aim to heal scleroderma finger sores

NCT ID NCT04356755

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether injecting a patient's own cultured fat stem cells into stubborn finger ulcers can help them heal. The study includes 32 adults with scleroderma who have at least one ulcer that hasn't healed with standard care. Half get stem cell injections, half get a placebo, and they are followed for 16 weeks to see if the ulcers shrink or close completely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cultured adipose-derived stem cells (AdMSC)

What this could lead to

If it works, this could offer a new way to heal painful finger ulcers in scleroderma patients who have no other options.

What could go wrong

This is a small, early-phase trial with only 32 people. The treatment may not work better than placebo, and there are risks like infection or worsening ulcers.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Toulouse - Hôpital PURPAN-TSA

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Grenoble Hospital

    NOT_YET_RECRUITING

    Grenoble, France

    Contact

  • Lille Hopsital

    NOT_YET_RECRUITING

    Lille, France

    Contact

  • Marseille Hospital

    NOT_YET_RECRUITING

    Marseille, France

    Contact

  • Montpellier Hospital

    NOT_YET_RECRUITING

    Montpellier, France

    Contact

  • Nantes Hospital

    NOT_YET_RECRUITING

    Nantes, France

    Contact

  • Poitiers Hospital

    NOT_YET_RECRUITING

    Poitiers, France

    Contact