Stem cell shots aim to heal scleroderma finger sores

NCT ID NCT04356755

Recruiting now Disease control Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether injecting a patient's own cultured fat stem cells into stubborn finger ulcers can help them heal. The study includes 32 adults with scleroderma who have at least one ulcer that hasn't healed with standard care. Half get stem cell injections, half get a placebo, and they are followed for 16 weeks to see if the ulcers shrink or close completely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cultured adipose-derived stem cells (AdMSC)
What this could lead to: If it works, this could offer a new way to heal painful finger ulcers in scleroderma patients who have no other options.
What could go wrong: This is a small, early-phase trial with only 32 people. The treatment may not work better than placebo, and there are risks like infection or worsening ulcers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

systemic sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYSTEMIC SCLEROSIS

Contacts and locations

Locations

CHU de Toulouse - Hôpital PURPAN-TSA
RECRUITING

Toulouse, 31059, France
Grenoble Hospital
NOT_YET_RECRUITING

Grenoble, France
Lille Hopsital
NOT_YET_RECRUITING

Lille, France
Marseille Hospital
NOT_YET_RECRUITING

Marseille, France
Montpellier Hospital
NOT_YET_RECRUITING

Montpellier, France
Nantes Hospital
NOT_YET_RECRUITING

Nantes, France
Poitiers Hospital
NOT_YET_RECRUITING

Poitiers, France

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