Mini eyes grown in lab to unlock secrets of birth defects

NCT ID NCT06408701

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study takes skin or blood cells from 20 people with eye malformations and turns them into stem cells, which are then grown into tiny 3D eye-like structures (organoids) in a dish. Researchers will study these mini eyes to understand what goes wrong during development and test new treatments. The goal is to learn more about the genetic causes of these conditions, not to directly treat participants.

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Conditions

The condition(s) this trial relates to.

aniridia Anophthalmos coloboma Eye Abnormalities microphthalmia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Clermont-Ferrand - Hôpital d'Estaing

    RECRUITING

    Clermont-Ferrand, France

  • Purpan University Hospital

    RECRUITING

    Toulouse, 31059, France