Cream wraps could soothe painful skin for ichthyosis patients
NCT ID NCT05979506
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a series of three cream wraps can reduce skin discomfort in people with moderate to very severe hereditary ichthyosis. Participants will receive a therapeutic bath followed by application of a rich emollient cream and a plastic wrap for one hour. The main goal is to see if at least a 3-point reduction in skin discomfort is achieved 11 days after treatment. The study enrolls 34 people and is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- emollient cream and urea cream applied under occlusion (wraps)
- What this could lead to
- If it works, this could offer a simple, nurse-led way to ease painful skin discomfort for people with ichthyosis.
- What could go wrong
- This is a small, early study (34 people) with no control group, so results may not apply to everyone. The benefit may be short-lived or no better than standard creams.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Toulouse University hospital
RECRUITINGToulouse, 31059, France
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