Cream wraps could soothe painful skin for ichthyosis patients

NCT ID NCT05979506

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a series of three cream wraps can reduce skin discomfort in people with moderate to very severe hereditary ichthyosis. Participants will receive a therapeutic bath followed by application of a rich emollient cream and a plastic wrap for one hour. The main goal is to see if at least a 3-point reduction in skin discomfort is achieved 11 days after treatment. The study enrolls 34 people and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

emollient cream and urea cream applied under occlusion (wraps)

What this could lead to

If it works, this could offer a simple, nurse-led way to ease painful skin discomfort for people with ichthyosis.

What could go wrong

This is a small, early study (34 people) with no control group, so results may not apply to everyone. The benefit may be short-lived or no better than standard creams.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ichthyosis inherited ichthyosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Toulouse University hospital

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••