Tiny brain signals may guide better seizure surgery
NCT ID NCT06105645
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether measuring a specific type of brain wave called 'fast-ripples' can help surgeons do a better job treating drug-resistant epilepsy. About 440 patients will have brain monitoring with special electrodes before surgery. Half will have fast-ripple information used to plan their surgery, and half will not. The goal is to see if the fast-ripple group has fewer seizures one year after the operation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DIXI Medical Microdeep® Micro-Macro Depth electrodes
What this could lead to
If successful, this could show that using fast-ripple information helps surgeons better identify and remove the seizure-causing brain tissue, leading to more patients being seizure-free after surgery.
What could go wrong
This is an early exploratory study, not a randomized trial. The benefit of fast-ripples is not yet proven, and the results may not apply to all epilepsy patients. There are also standard surgical risks like infection or bleeding.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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APHP Hôpital Bicêtre
RECRUITINGLe Kremlin-Bicêtre, 94270, France
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CHRU de Nancy
RECRUITINGNancy, France
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CHU Amiens Picardie
RECRUITINGAmiens, France
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CHU de Lille
RECRUITINGLille, France
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CHU de Rennes
RECRUITINGRennes, France
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Fondation Adolphe de Rothschild
NOT_YET_RECRUITINGParis, 75019, France
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Hospices Civils de Lyon
RECRUITINGLyon, France
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Hôpitaux universitaires de Strasbourg
RECRUITINGStrasbourg, France
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University Hospital of Toulouse
RECRUITINGToulouse, 31059, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University hospital of Bordeaux
RECRUITINGBordeaux, 33076, France
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University hospital of Grenoble Alpes
RECRUITINGLa Tronche, 38700, France
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