Can mindfulness rewire the mind to lift depression in epilepsy?

NCT ID NCT06865820

Recruiting now Symptom relief Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study tests whether a mindfulness-based program called Project UPLIFT can help adults with epilepsy feel less depressed and enjoy a better quality of life. Participants attend weekly group sessions over 8 weeks, delivered remotely by phone or video. The program teaches skills like challenging negative thoughts, coping, problem-solving, and mindfulness. Researchers will also look at whether the program is worth its cost.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Project UPLIFT, a mindfulness-based cognitive behavioral therapy program delivered in weekly group sessions over 8 weeks via phone or video
What this could lead to: If effective, this program could offer a practical, low-cost way to improve mental health and quality of life for many people living with epilepsy.
What could go wrong: This is a small study, and results may not apply to everyone. The program's success depends on participants' engagement, and it may not work for all individuals.

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Conditions

The condition(s) this trial relates to.

epilepsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EPILEPSY

Contacts and locations

Locations

Rollins School of Public Health
RECRUITING

Atlanta, Georgia, 30322, United States

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