A break from seizure pills: could less medication mean better living?

NCT ID NCT07750496

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study looks at what happens when people with epilepsy who have been seizure-free for at least two years stop one of their antiseizure medications. The goal is to see if coming off the drug improves quality of life and reduces side effects, without greatly increasing the risk of seizures. Participants will be followed for about a year, with visits conducted mostly by video. The findings could help guide future decisions about whether and how to taper epilepsy medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Discontinuation of antiseizure medication
What this could lead to
If successful, this could help doctors and patients decide whether stopping epilepsy medication is safe and beneficial after a long seizure-free period.
What could go wrong
The study is small and early, and stopping medication may increase the risk of seizures. Results may not apply to all epilepsy patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

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