New heat therapy could replace surgery for Hormone-Fueled hypertension
NCT ID NCT07470580
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two treatments for a condition called primary aldosteronism, where a small adrenal gland tumor causes high blood pressure. One treatment is laparoscopic surgery to remove the tumor; the other is radiofrequency ablation (RFA), which uses heat delivered through a needle to destroy the tumor. The goal is to see if RFA works as well as surgery to normalize blood pressure and hormone levels, with fewer side effects. About 134 adults with a confirmed adrenal adenoma will be randomly assigned to one of the two procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiofrequency ablation (RFA) procedure
- What this could lead to
- If RFA works as well as surgery, patients could avoid an operation and have a quicker recovery with fewer complications.
- What could go wrong
- This is a relatively new use of RFA for this condition, and it may not be as effective as surgery in the long term. The trial is still recruiting, so results are not yet available.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital of Toulouse
RECRUITINGToulouse, France
More trials for these conditions
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