Can retraining word meanings restore lost speech?
NCT ID NCT04957537
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This study tests whether a specialized speech therapy that focuses on word meanings can help people with mild-to-moderate semantic aphasia—a condition where brain damage impairs understanding and use of words. Participants first undergo a control period of standard language exercises, then receive the semantic training in multiple sessions. Researchers measure improvements in naming accuracy and speed, and check if gains last a month later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A structured speech therapy program focused on semantic training (analyzing word meanings) compared with a control phase of lexico-phonological exercises.
- What this could lead to
- If effective, this therapy could help people with semantic aphasia regain word-finding ability and slow language decline, improving daily communication.
- What could go wrong
- This is a very small early-stage study (15 people) without a control group, so results may not generalize. Benefits may be modest or not persist after therapy ends.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Toulouse
RECRUITINGToulouse, France
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