PRIMARY PROGRESSIVE APHASIA
Clinical trials for PRIMARY PROGRESSIVE APHASIA explained in plain language.
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Brain zaps may boost speech in progressive aphasia
Symptom relief Recruiting nowThis study tests a safe, painless brain stimulation technique called tDCS to see if it can improve language skills in people with primary progressive aphasia (PPA), a condition that slowly destroys the ability to speak and understand language. Researchers will compare real tDCS t…
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 16, 2026 23:34 UTC
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Zapping the brain to fight Dementia's theft of speech
Symptom relief Recruiting nowThis study is testing whether a gentle, non-invasive form of electrical brain stimulation can help improve language and memory problems in people with a specific type of dementia called logopenic variant primary progressive aphasia (lvPPA). Researchers will combine the brain stim…
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 20, 2026 16:19 UTC
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Mayo clinic launches study to unravel speech disorder mysteries
Knowledge-focused Recruiting nowThis study aims to identify and distinguish two different types of Progressive Apraxia of Speech, a condition that affects a person's ability to speak clearly. Researchers at Mayo Clinic will use clinical imaging and testing on 47 participants to better understand these speech pr…
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 16, 2026 23:33 UTC
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Researchers use brain scans to track speech decline
Knowledge-focused Recruiting nowThis study looks at how brain changes relate to speech and language problems in people with progressive apraxia of speech (AOS). About 50 participants will have regular brain scans and speech tests over time. The goal is to better understand the disease, not to test a treatment.
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Phase: PHASE4 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Scientists track brain shrinkage and speech decline in rare language disorder
Knowledge-focused Recruiting nowThis study watches how the brain shrinks unevenly and how language skills fade over time in people with primary progressive aphasia. Researchers will not give any treatment, but will use brain scans and language tests to learn more about the disease. The study needs 500 right-han…
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Blood tests could predict dementia progression in new study
Knowledge-focused Recruiting nowThis study aims to better predict how dementia will progress in individuals with mild cognitive impairment or early dementia. Researchers will collect blood samples and use computer models to track changes in thinking and memory over time. The goal is to improve prognostic confid…
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Can two languages shield the brain? new study targets bilingual aphasia
Knowledge-focused Recruiting nowThis study looks at whether being bilingual helps people with primary progressive aphasia (PPA) respond better to speech therapy. Researchers will give tailored language treatment in both languages to 60 bilingual Spanish speakers and track their progress for a year. Another 30 p…
Matched conditions: PRIMARY PROGRESSIVE APHASIA
Phase: NA • Sponsor: University of Texas at Austin • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC