New PET tracer could spot brain inflammation in autoimmune encephalitis

NCT ID NCT07488117

Recruiting now Diagnosis Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special PET scan tracer called [18F]-DPA-714 can detect brain inflammation in people with autoimmune encephalitis (AE). Researchers will compare scans from 40 newly diagnosed AE patients to healthy volunteers. If the tracer works well, it could become a new tool for diagnosing and tracking this rare brain condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: [18F]-DPA-714 (a radioactive tracer for PET imaging)
What this could lead to: If successful, this imaging method could help doctors diagnose and monitor brain inflammation in autoimmune encephalitis more accurately.
What could go wrong: This is a small early-phase study (40 people) focused on imaging, not treatment. The tracer may not clearly distinguish patients from healthy controls.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune disorder of the nervous system autoimmune encephalitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE ENCEPHALITIS (AE)

Contacts and locations

Locations

University Hospital
RECRUITING

Toulouse, France

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