Experimental cell therapy takes aim at Hard-to-Treat autoimmune diseases

NCT ID NCT07526493

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing a new cell therapy called QH103 for people with severe autoimmune diseases like multiple sclerosis and myasthenia gravis that haven't responded to standard treatments. The therapy uses specially engineered immune cells to target and attack the faulty immune cells causing the disease. Only 6 participants will be enrolled to check for safety and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QH103 cell injection (genetically modified immune cells targeting CD19)

What this could lead to

If successful, this could point toward a new treatment option for people with hard-to-treat autoimmune diseases that attack the nervous system.

What could go wrong

This is a very early, small phase 1 trial with only 6 participants, so safety and effectiveness are not yet known. There are risks of serious side effects like cytokine release syndrome or graft-versus-host disease.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired idiopathic inflammatory myopathy autoimmune disorder of the nervous system autoimmune encephalitis chronic inflammatory demyelinating polyradiculoneuropathy multiple sclerosis myasthenia gravis myelin oligodendrocyte glycoprotein antibody-associated disease myositis disease neuromyelitis optica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact

    Contact

    Contact