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Engineered immune cells take on multiple sclerosis and other autoimmune brain diseases

NCT ID NCT07337785

Recruiting now Disease control Sponsor: Tongji Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a new treatment called RD06-05, which uses specially engineered immune cells (CAR-T cells) to target and calm the immune system in people with neurological autoimmune diseases like multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, and autoimmune encephalitis. The main goal is to check if the treatment is safe and to find the right dose. About 24 to 36 adults aged 18 to 70 will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

autoimmune disorder of the nervous system autoimmune encephalitis chronic inflammatory demyelinating polyradiculoneuropathy multiple sclerosis myasthenia gravis primary progressive multiple sclerosis Recurrence relapsing-remitting multiple sclerosis secondary progressive multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTOIMMUNE ENCEPHALITIS (AE) CHRONIC INFLAMMATORY DEMYELINATING POLYNEUROPATHY (CIDP) MYASTHENIA GRAVIS (MG) RELAPSING OR REFRACTORY MULTIPLE SCLEROSIS (MS)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••