University Hospital, Toulouse

This study tested whether adding a pharmacist to a hospital's mobile geriatric team could help improve medication safety for elderly patients. The team reviewed the drug lists of patients aged 75+ who were taking five or more daily medications. The goal was to identify and reduce…

This study compared two different drug combinations used right after a kidney transplant to prevent the body from rejecting the new organ. It focused on patients at high risk for rejection because their immune systems were already 'sensitized' to foreign tissue. The goal was to s…

This study tested whether a 6-month home program using a website and connected devices was practical and acceptable for older adults. The program combined nutritional advice, physical exercise, and brain training games, all done remotely. Researchers wanted to see if this approac…

This study tested whether treating gum disease helps improve blood sugar control in people with diabetes. Researchers divided 91 diabetic patients with gum disease into two groups: one received immediate gum treatment, while the other received delayed treatment after the study. T…

This small, early-stage study tested whether a hormone called apelin can improve how the body uses insulin in people with type 2 diabetes. Nine volunteers with well-controlled diabetes received a continuous infusion of apelin or a placebo. The main goal was to see if apelin made …

This study investigated whether a standard daily low-dose aspirin pill is enough to prevent blood clots in adults who have both a rare bleeding disorder (immune thrombocytopenia) and heart disease. Researchers measured how well aspirin worked in the body 24 hours after a dose in …

This study tested if a single dose of the drug tocilizumab, given around the time a failed kidney transplant is surgically removed, is safe and can help reduce harmful antibodies. These antibodies often form after removal and make it very difficult for patients to receive a secon…

This study tested a new way to prevent blood from clotting in the dialysis machine for critically ill patients who are at high risk of bleeding. It compared a new method using a special, calcium-free dialysis fluid against the standard method using a special membrane. The goal wa…

This study tested whether a newer blood-thinning drug (ticagrelor) works better than a standard one (clopidogrel) during a procedure to clear severely hardened heart arteries. Researchers enrolled 180 patients with stable heart disease to see if the newer drug reduces heart muscl…

This small study tested a new, combined procedure for people with complex, long-lasting atrial fibrillation (AF) that hasn't responded to medication. Doctors performed both a minimally invasive surgery and a catheter-based procedure at the same time to try to block the faulty ele…

This study tested whether using phone and video calls (telemedicine) to monitor patients during chemotherapy for aggressive lymphoma helps them better tolerate their full treatment doses. It involved 350 patients across 10 hospitals, comparing those receiving standard in-person c…

This study tested whether lixisenatide, a drug used for type 2 diabetes, could slow the worsening of movement problems in people with early Parkinson's disease. 156 participants received either the drug or a placebo as a daily injection for one year, in addition to their standard…

This study tested two different approaches to help rheumatoid arthritis patients safely stop taking steroid medications. Researchers compared gradually reducing steroids versus switching to a different steroid type in 102 patients whose arthritis was already well-controlled. The …

This study looked at whether using quick urine drug tests in a family doctor's office helps people stay in treatment for opioid addiction. It involved 42 patients starting a medication called buprenorphine. The main goal was to see if patients who had these on-site tests stayed i…

This small study tested whether treating gum disease (periodontitis) could help reduce the severity of rheumatoid arthritis (RA) in people who have both conditions. Researchers enrolled 22 patients with both RA and gum disease to see if professional dental cleaning and treatment …

This study tested a new laboratory method to improve the diagnosis of rare, inherited platelet disorders that cause bleeding problems. Researchers enrolled 322 patients with various bleeding conditions to see if a faster test using a small blood sample could reliably identify har…

This study tested whether a special PET-CT scan could predict if surgery to extract sperm directly from the testicles would be successful in men with a condition called azoospermia (no sperm in semen). Researchers compared scan results from 160 men who had successful sperm extrac…

This study tested whether doctors could collect heart muscle cells during a standard heart mapping procedure and use their DNA to improve genetic testing for a rare heart condition called arrhythmogenic right ventricular cardiomyopathy (ARVC). Researchers worked with 34 patients …

This study tested a new, radiation-free method to monitor scoliosis in children. Researchers compared a 3D surface scan to standard X-rays to see if it could measure spinal curves just as accurately. The goal was to find a safer way to track the condition over time without repeat…

This study compared two imaging methods—CT scans and cone beam imaging—for diagnosing sinus problems. Researchers tested both methods on 50 adults with sinus symptoms to see if they produced similar results. The main goal was to determine if cone beam imaging, which uses less rad…

This study looked at whether hydroxychloroquine, a medication many lupus patients take long-term, might have helped protect them from catching COVID-19 or getting severely ill during the pandemic. Researchers compared over 550 lupus patients who were already taking the drug to si…

This study tested whether a special nurse visit after an older adult falls at home and calls emergency services could help them live longer and stay in their own home. Researchers enrolled 952 seniors who were not hospitalized after their fall. A nurse visited them to assess fall…

This study tested whether a small, flexible ring placed in the vagina (called a pessary) could help prevent premature birth in twin pregnancies where the mother's cervix is found to be short. It involved 324 women in France with twin pregnancies. The goal was to see if using the …

This study tested whether a special training program for hospital staff could help prevent older patients from losing their ability to care for themselves during a hospital stay. Researchers compared two hospital units—one using standard care and one where staff received training…

This study tested whether using ultrasound to guide numbing injections near specific nerves could better control pain after corrective jaw surgery. Researchers compared this nerve block approach to standard local numbing in 50 patients undergoing the procedure. The main goal was …

This study tested two ways to reduce the pain children feel when a common anesthesia drug is given through an IV. Researchers compared a special hypnosis technique called the 'magic glove' to a standard numbing medicine (lidocaine). They enrolled 100 children aged 7 to 14 to see …

This small pilot study tested whether adjusting the settings on an existing deep brain stimulator could help Parkinson's patients with a severe walking problem called freezing of gait. Ten patients who already had the brain implant tried three different stimulation patterns over …

This study tested whether a long-term exercise program could help people with moderate to severe dementia living in nursing homes maintain their ability to perform daily tasks like bathing and dressing. It compared a group doing regular exercise to a control group participating i…

This study looked at whether adding a special massage treatment called LPG Cellu M6 could help reduce arm swelling (lymphedema) in breast cancer survivors. Researchers compared standard bandage therapy alone to bandage therapy combined with the massage device. The goal was to see…

This study tested whether a mindfulness-based group therapy program, originally developed in Canada, could be successfully run for teenagers with chronic pain in France. The main goal was to see if the program was practical and if teens would attend the sessions. Researchers also…

This study tested whether using a special low-power laser is a practical way to treat painful mouth sores in children receiving cancer therapy. It involved 22 children in a hospital in France to see if the laser treatment could be consistently delivered and if it helped reduce th…

This study tested whether gentle electrical stimulation of a nerve near the ankle could improve bladder control problems in people with Parkinson's disease. 110 participants used either the real stimulation device or a placebo device for 20 minutes daily over 3 months. Researcher…

This study tested a specific supportive sling device for adults recovering from a recent stroke. The goal was to see if using the sling could help prevent shoulder pain and complications, improve arm function, and enhance quality of life. Researchers enrolled 25 participants to m…

This study tested whether oxytocin, a hormone sometimes called the 'love hormone,' given as a nasal spray could improve behavior and social skills in adults with Prader-Willi syndrome. Researchers enrolled 50 adults with genetically confirmed Prader-Willi syndrome to see if the t…

This study tested whether adding a new type of nerve block, called a PENG block, to standard pain control methods could better manage pain after hip replacement surgery. Researchers enrolled 64 patients to see if this block could reduce the need for strong painkillers like morphi…

This study tested whether a personalized physical training program could help people with ankylosing spondylitis, a condition that causes painful stiffness in the spine and joints. 56 participants were randomly assigned to either follow the exercise program or just receive inform…

This study looked at whether a specific nerve block used to control pain after shoulder surgery causes temporary weakness in the main breathing muscle (the diaphragm). Researchers compared two different injection approaches for the nerve block in 84 patients to see if one was les…

This study tested whether a robotic walking aid called SAFEWALKER could help older adults recover from 'post-fall syndrome'—a condition involving fear of falling and difficulty walking. Researchers wanted to see if using the robot alongside standard physical therapy was practical…

This study tested whether adding a specific nerve block (called iPACK) to standard pain control improves recovery after ACL knee surgery. Researchers compared two groups of 90 adults having surgery: one received the combined nerve blocks, while the other received the standard blo…

This study tested a portable seat insert designed to improve posture and help people with swallowing difficulties. It involved 64 adults who had trouble swallowing and also had poor sitting posture. Researchers compared how well people swallowed after one month of using the speci…

This study tested if a personalized exercise program could help children and young adults with Marfan syndrome. Researchers wanted to see if the training could improve muscle strength, physical endurance, and overall quality of life for the 28 participants. The goal was to find a…

This study aimed to understand how well two different types of heart stents heal inside arteries after a severe heart attack. Researchers enrolled 22 patients who had a heart attack and needed a stent. They used a special imaging camera inside the artery to see how the stents wer…

This study aims to understand how children develop thinking skills and social abilities years after having heart surgery as infants. Researchers are asking parents of children aged 6-18 who had heart surgery before three months old to complete questionnaires about their child's b…

This study tested if a 'Learning from Excellence' program could improve the quality of care in a pediatric intensive care unit. The program encouraged staff to share and learn from positive experiences and successes. Researchers measured if this approach increased parent satisfac…

This study aimed to translate and test a French version of a questionnaire about male sexual dysfunction. Researchers wanted to see if the translated questions were easy for French-speaking patients to understand. The study did not test any treatments; it only gathered informatio…

This study aimed to understand how metabolism works in children with Noonan syndrome, a rare genetic condition. Researchers compared 20 children with the syndrome to healthy children, measuring things like insulin sensitivity and body fat. The goal was to gather basic knowledge, …

This study aimed to understand why some people experience confusion and memory problems after surgery, a condition known as post-operative cognitive dysfunction (POCD). Researchers followed 115 patients having hip or heart surgery to see if inflammation from body fat, especially …

This study aimed to understand how Polycystic Ovary Syndrome (PCOS) affects women's sexual health and emotional well-being. Researchers compared 84 women—some with PCOS and some without—by having them complete online surveys about sexual function, body image, anxiety, and depress…

This study aimed to understand how a rare and severe brain infection called PML might weaken the body's immune defenses. Researchers followed 22 patients to see if specific markers on immune cells were linked to how well their bodies could fight the virus and their recovery. The …

This study examined whether surgical abortions performed between 14-16 weeks of pregnancy carry different risks than those done earlier (10-14 weeks). Researchers followed 312 women to compare bleeding risks and measure anxiety levels. The goal was to provide better information t…

This study looked at whether doctors could successfully plan for children's anesthesia using video calls instead of in-person visits during the COVID-19 pandemic. Researchers wanted to see if this remote method was practical and worked well for families and medical teams. The goa…

This study aimed to understand how often people with hereditary ichthyosis, a rare genetic skin condition, develop early signs of an eye condition called keratoconus. Researchers compared 152 people with ichthyosis to healthy individuals using special eye imaging tests. The goal …

This study surveyed 47 adults aged 65 and older in France to understand how many use non-medical cannabidiol (CBD) and what they know about it. Researchers wanted to map out usage trends and identify potential knowledge gaps, especially regarding safety and drug interactions in a…

This study aimed to understand if the act of surgically removing a pancreatic tumor causes tumor DNA to be released into the patient's bloodstream. Researchers tracked 35 patients with operable pancreatic cancer, taking blood samples before, during, and for a year after surgery. …

This study tested a new type of tiny brain electrode to see if it could reliably record very fast brain signals called 'fast ripples' in people with hard-to-treat epilepsy. Researchers wanted to know if these signals could help pinpoint the exact brain area causing seizures, whic…

This study aimed to understand if damage to a man's sperm DNA might be a factor in couples who experience multiple unexplained miscarriages. Researchers compared 64 men: some from couples with recurrent pregnancy loss and others from couples who had a successful pregnancy. The ma…

This study tested whether special educational workshops could change how people with Parkinson's disease think and feel about their medications. Researchers compared 24 patients who attended a workshop about Parkinson's drugs to a control group who had general discussions. They m…

This study tested whether children with cochlear implants and their families would accept using a humanoid robot at home for a month. The goal was to see if a robot could provide helpful, fun, at-home practice to supplement regular speech therapy sessions. Researchers measured ho…

This study aimed to find early warning signs in a patient's immune system that predict if their COVID-19 will get worse. Researchers analyzed blood samples from 304 people with COVID-19, including hospitalized patients and healthcare workers with milder cases. The goal was to ide…

This study aimed to discover proteins in spinal fluid that could help doctors better understand and diagnose Normal Pressure Hydrocephalus and related brain conditions. Researchers analyzed spinal fluid from 100 patients who had symptoms like walking problems, memory issues, and …

This study aimed to understand if a specific sign seen on brain MRI scans, called cortical superficial siderosis, can predict which patients with cerebral amyloid angiopathy (CAA) are more likely to have another symptomatic brain bleed. Researchers followed 170 older adults who h…

This small pilot study aimed to gather information on how two common treatments for otosclerosis—a hearing aid and surgery—affect patients' quality of life and hearing. Thirty patients with this type of hearing loss first tried a hearing aid for two months and then had surgery. R…

This study looked at how strictly nursing homes in France followed COVID-19 safety rules, like visitor bans and room confinement, and whether that affected how many residents died. Researchers tracked over 12,000 residents for a year to see if strong rules lowered COVID deaths bu…

This study aimed to understand what happens to people's lungs months after they recover from severe COVID-19 pneumonia. Researchers followed 73 patients who had been hospitalized with COVID-19, checking their breathing and lung function four months later. The goal was to identify…

This study used brain scans to understand how the brain adapts when someone with severe hearing loss in one ear gets a cochlear implant. Researchers compared 20 people with implants to people with normal hearing while they listened to sounds. The goal was to see how the brain pro…

This study aimed to understand how tiny blood cells called platelets become overactive in people with septic shock, a life-threatening condition. Researchers compared blood samples from 27 patients in intensive care with septic shock to samples from people having routine knee or …

This study aimed to understand how caregivers help people with Parkinson's disease who have difficulty swallowing eat their meals. Researchers filmed and interviewed 22 patient-caregiver pairs during mealtimes to learn about their strategies for balancing safety, nutrition, and e…

This study aims to understand how surgery to remove the bladder for cancer affects patients' sexual quality of life in the long term. Researchers followed 50 patients, asking them to complete detailed questionnaires about their sexual function and overall well-being before their …

This small study aimed to find out if the dengue virus can be present in semen during an active infection. Researchers tested 10-15 men with confirmed dengue to see if the virus was in their sperm and if standard sperm washing techniques could remove it. The goal was to better un…

This study aimed to better understand how the gut repairs itself in people with inflammatory bowel disease (like Crohn's or colitis) and a condition called familial polyposis. Researchers grew tiny 3D models of the gut, called organoids, from small tissue samples taken during rou…

This study tested a new ultrasound method called the VExUS score to see if it could accurately measure changes in blood volume in children. Researchers enrolled 67 children aged 1 to 18 who were having medical procedures that significantly changed their blood volume, like fluid r…

This study aimed to understand why many lupus patients don't consistently take their Plaquenil (hydroxychloroquine) medication as prescribed. Researchers surveyed 102 adult lupus patients who had been on the medication for over six months. They tested a questionnaire to help doct…