PROSTATE CANCER DIAGNOSIS

This early-stage study tests two types of targeted radiation therapy (177Lu-PSMA-617 and 225Ac-PSMA-617) in 45 men with high-risk prostate cancer who are scheduled for prostate removal surgery. The goal is to see which therapy delivers more radiation to the tumor and how it affec…

This study tests if a daily pill (abiraterone with prednisone) can lower testosterone enough to control prostate cancer, without using standard hormone-blocking injections. About 60 men with advanced prostate cancer who need stronger hormone therapy will take the pill and be moni…

This study tests a new robot and ultrasound probe, called ProBot, designed to make prostate biopsies more accurate and comfortable. It involves 60 men aged 40-75 with high-risk features like elevated PSA or abnormal exams. The goal is to see if the device is safe and works well f…

This study tests whether new types of MRI scans can more accurately detect and grade prostate cancer without using contrast dye. Researchers will compare these advanced scans with standard MRI and biopsy results in 300 men with suspected prostate cancer. The goal is to improve di…

This study is testing a new blood test that looks at proteins in platelets (a type of blood cell) to see if it can find prostate cancer more accurately than current methods like PSA tests and biopsies. Researchers will enroll 300 men who are already being checked for prostate can…

This study tests whether combining PSMA PET scans with machine learning can accurately determine how aggressive a prostate cancer is without needing invasive biopsies. Researchers will scan 220 men with suspected or known prostate cancer and use AI to predict the cancer's Gleason…

This study aims to create a blood test that uses genetic material from tiny particles (exosomes) to predict if prostate cancer has spread to the bones. Researchers will enroll 1000 men with newly diagnosed prostate cancer to develop and validate the test, comparing it to standard…

This study tests a new way to decide who needs a prostate biopsy. Instead of relying only on MRI, it adds a blood test called Prostate Health Index (PHI) to better tell which men have dangerous prostate cancer. The goal is to safely skip biopsies in men who don't need them, reduc…

This study aims to see if a new type of PET/CT scan that targets a protein called ACP3 can find prostate cancer tumors as well as or better than current scans. About 100 adults with newly diagnosed or recurring prostate cancer will receive both the new ACP3 scan and standard PSMA…

This study compares two ways of taking prostate biopsies to see which finds dangerous cancers more accurately while avoiding unnecessary detection of harmless ones. About 592 men with a suspicious MRI finding will get either targeted plus perilesional biopsies or a combination th…

This study tests whether a digital exercise program with virtual group sessions helps prostate cancer patients on hormone therapy stick to their exercise goals. Hormone therapy can cause fatigue, muscle loss, and weight gain, but exercise can help. The trial will compare the digi…

This study tests a new program for prostate cancer patients about to start hormone therapy and radiation. The program includes 12 weeks of exercise and a 4-day residential workshop with education and activities. Researchers want to see if patients and their families find it helpf…

This study looks at how well a virtual oncology program works for veterans newly diagnosed with lung, colorectal, prostate, or breast cancer. Researchers will track telehealth visits, quality of care, and costs over 36 months. The goal is to see if this program helps veterans get…

This study looks at whether adding a PSMA PET scan to the usual MRI scan can better find prostate cancer that has come back after focal therapy (a treatment that targets only the tumor). About 62 men who have had focal therapy will get both scans. The goal is to see if the PSMA P…

This study is for men with prostate cancer who are getting a type of radiation called brachytherapy. Researchers want to see how the immune system changes during treatment. They will take blood and tissue samples before, during, and after the procedure. The goal is to learn more,…

This study follows 100 men who had a prostate MRI showing suspicious spots but no significant cancer on their first biopsy. Researchers will repeat MRI scans and biopsies over time to see if changes in those spots can predict future cancer. The goal is to better understand which …

This study aims to describe the characteristics of prostate cancer in Algeria, including patient demographics, symptoms, diagnosis methods, and treatments. Researchers will collect information from 2,000 patients aged 19 and older with confirmed prostate cancer. The goal is to be…

This study follows 500 men who had their prostate removed for cancer. Researchers check PSA levels soon after surgery to see if they can predict if the cancer will come back or spread. No new treatments are given—just standard care and observation.