New hope for High-Risk prostate cancer: which targeted radiation works best?

NCT ID NCT07054346

Recruiting now Disease control Sponsor: Thomas Hope Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests two types of targeted radiation therapy (177Lu-PSMA-617 and 225Ac-PSMA-617) in 45 men with high-risk prostate cancer who are scheduled for prostate removal surgery. The goal is to see which therapy delivers more radiation to the tumor and how it affects the immune system. Participants will receive one of the treatments before surgery, and researchers will measure the radiation dose in the tumor and any side effects.

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Conditions

The condition(s) this trial relates to.

disease prostate adenocarcinoma prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIGH RISK PROSTATE CANCER LOCALIZED PROSTATE CARCINOMA PROSTATE CANCER PROSTATE CANCER (DIAGNOSIS) VERY HIGH RISK PROSTATE CARCINOMA

Contacts and locations

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Locations

University of California, San Francisco
RECRUITING

San Francisco, California, 94143, United States

Contact Email: •••••@•••••

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